PLXDC1 Protein, Mouse (P.pastoris, His)
Plexin domain-containing protein 1 (PLXDC1) is critical in endothelial cell capillary morphogenesis, interacting with NID1 and possibly binding to CTTN. These interactions implicate its broader involvement in cellular responses and multiple cellular functions within the extracellular matrix. PLXDC1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Plexin domain-containing protein 1 protein, expressed by P. pastoris , with N-His labeled tag.
- Species: Mouse
- Source: P. pastoris
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Biological Activity
Description
Plexin domain-containing protein 1 (PLXDC1) is critical in endothelial cell capillary morphogenesis, interacting with NID1 and possibly binding to CTTN. These interactions implicate its broader involvement in cellular responses and multiple cellular functions within the extracellular matrix. PLXDC1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Plexin domain-containing protein 1 protein, expressed by P. pastoris , with N-His labeled tag.
Background
The Plexin Domain-Containing Protein 1 (PLXDC1) plays a crucial role in the intricate process of endothelial cell capillary morphogenesis. Its significance is underscored by its interaction with NID1, suggesting a potential involvement in mediating cellular responses within the extracellular matrix environment. Furthermore, PLXDC1 may engage with CTTN, implying a broader spectrum of protein interactions that could contribute to diverse cellular functions. The precise mechanisms by which PLXDC1 modulates endothelial cell capillary morphogenesis and its interactions with NID1 and CTTN warrant further exploration, shedding light on the intricate regulatory networks involved in angiogenesis and tissue morphogenesis.
Technical Parameters
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Species Mouse
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Source P. pastoris
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Tag N-His
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Accession
Q91ZV7-1 (L20-T426)
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Molecular Construction
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N-term
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His
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PLDX1 (L20-T426)
Accession # Q91ZV7-1 -
C-term
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Protein Length
Extracellular Domain
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Synonyms
PLXDC1; Tumor Endothelial Marker 7; Plexin Domain Containing 1; CDNA FLJ58221, Highly Similar To Plexin Domain-Containing Protein 1; TEM3; Tumor Endothelial Marker 7 Precursor; TEM7; Alternative Protein PLXDC1; Plexin Domain-Containing Protein 1; 2410003I
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AA Sequence
LSPATPAGHNEGQDSAWTAKRTRQGWSRRPRESPAQVLKPGKTQLSQDLGGGSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEKQSQDLWVDLAVANRSHVKIHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDMLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQDREDRGSFTFQAALHRDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPASQRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDTCVSSNLTFNCSWCHVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEDFQDDSHYSASPDSSFSPFNGDSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDHSSPKSKGPPVHLGT
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Predicted Molecular Mass
47.3 kDa
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)