PNLIPRP1 Protein, Rat (HEK293, His)
Based on 1 Customer Validation
PNLIPRP1 Protein, a potential inhibitor of dietary triglyceride digestion, likely modulates lipid metabolism. In vitro analyses reveal its lack of detectable lipase activity, suggesting a unique role as an enzyme inhibitor rather than an active participant in triglyceride hydrolysis. This characteristic underscores PNLIPRP1's potential regulatory impact on lipid digestion processes. PNLIPRP1 Protein, Rat (HEK293, His) is the recombinant rat-derived PNLIPRP1 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Rat
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Biological Activity
Description
PNLIPRP1 Protein, a potential inhibitor of dietary triglyceride digestion, likely modulates lipid metabolism. In vitro analyses reveal its lack of detectable lipase activity, suggesting a unique role as an enzyme inhibitor rather than an active participant in triglyceride hydrolysis. This characteristic underscores PNLIPRP1's potential regulatory impact on lipid digestion processes. PNLIPRP1 Protein, Rat (HEK293, His) is the recombinant rat-derived PNLIPRP1 protein, expressed by HEK293 , with C-His labeled tag.
Background
The PNLIPRP1 Protein emerges as a potential inhibitor of dietary triglyceride digestion, showcasing its probable role in modulating lipid metabolism. Notably, it lacks detectable lipase activity in vitro, as suggested by similarity analyses. This characteristic hints at PNLIPRP1's unique function as an enzyme inhibitor rather than an active participant in triglyceride hydrolysis, providing valuable insights into its potential regulatory role in lipid digestion processes.
Technical Parameters
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Species Rat
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Source HEK293
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Tag C-His
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Accession
P54316 (K18-V473)
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Molecular Construction
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N-term
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PNLIPRP1 (K18-V473)
Accession # P54316 -
His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
PNLIPRP1; Triacylglycerol Lipase; Pancreatic Lipase Related Protein 1; Pancreatic Lipase; PLRP1; PL-RP1; Inactive Pancreatic Lipase-Related Protein 1
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AA Sequence
KEVCYDNLGCFSDAEPWAGTAIRPLKLLPWSPEKINTRFLLYTNENPTAFQTLQLSDPLTIGASNFQVARKTRFIIHGFIDKGEENWVVDMCKNMFQVEEVNCICVDWKKGSQTTYTQAANNVRVVGAQVAQMIDILVKNYSYSPSKVHLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQMSGHLDFFPNGGQSMPGCKKNALSQIVDIDGIWSGTRDFVACNHLRSYKYYLESILNPDGFAAYPCASYKDFESNKCFPCPDQGCPQMGHYADKFAGKSGDEPQKFFLNTGEAKNFARWRYRVSLILSGRMVTGQVKVALFGSKGNTRQYDIFRGIIKPGATHSSEFDAKLDVGTIEKVKFLWNNQVINPSFPKVGAAKITVQKGEERTEYNFCSEETVREDTLLTLLPCETSDTV
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Molecular Weight
Approximately 55-60 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (238 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)