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  4. PRL2A1 Protein, Rat (HEK293, His)

PRL2A1 Protein, Rat (HEK293, His)

Cat. No.: HY-P77465
Handling Instructions

The PRL2A1 protein shows specific expression in the placenta, highlighting its unique role in this reproductive organ. Notably, it showed high expression levels in the invasive trophoblast cells that line the central blood vessels of the placenta, suggesting that these key cells have specialized functions. PRL2A1 Protein, Rat (HEK293, His) is the recombinant rat-derived PRL2A1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PRL2A1 Protein, Rat (HEK293, His) is 199 a.a., with molecular weight of ~24 KDa.

For research use only. We do not sell to patients.

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Description

The PRL2A1 protein shows specific expression in the placenta, highlighting its unique role in this reproductive organ. Notably, it showed high expression levels in the invasive trophoblast cells that line the central blood vessels of the placenta, suggesting that these key cells have specialized functions. PRL2A1 Protein, Rat (HEK293, His) is the recombinant rat-derived PRL2A1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PRL2A1 Protein, Rat (HEK293, His) is 199 a.a., with molecular weight of ~24 KDa.

Background

The PRL2A1 protein is characterized by its specific expression in the placenta, with a particular emphasis on its high expression in invasive trophoblast cells lining the central placental vessel.This unique expression pattern suggests a specialized role for PRL2A1 in the context of placental function, likely playing a crucial role in processes related to trophoblast invasion and vascular development within the placenta. Given its localization in invasive trophoblast cells, PRL2A1 may contribute to the establishment and maintenance of the maternal-fetal interface, playing a key role in supporting the dynamic and intricate processes associated with placental development and function during pregnancy. Further research into the molecular functions of PRL2A1 in the placenta could unveil its specific contributions to reproductive biology and maternal-fetal health.

Species

Rat

Source

HEK293

Tag

C-6*His

Accession

Q9JII3 (V30-C228)

Gene ID

116474  [NCBI]

Molecular Construction
N-term
PRL2A1 (V30-C228)
Accession # Q9JII3
His
C-term
Synonyms
Prolactin-2A1; Placental prolactin-like protein M; PLP-M; Prlpm
AA Sequence

VPTCLVRNGRCFASLEEMLERAVGLSEEISKQALQLFTEFDNQYAQSKQLINKNFKKCHTSSLELPKPSSTSVQTHPITLLKIASKLLSAWKVPLNDLVNNLPSLKDIHPNILSKAREIEAKSAGLLEGVKSILIQMQNGDTEDENYPGWSGLASLQSENEDDRLFAYYNMIRCEGRETQKVETALKMVKCKISNENNC

Molecular Weight

Approximately 24 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

PRL2A1 Protein, Rat (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PRL2A1 Protein, Rat (HEK293, His)
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HY-P77465
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