Prothymosin alpha Protein, Rat (P.pastoris, His)
Based on 1 publication(s) in Google Scholar
Thymosin alpha protein is a multifunctional player that may mediate immune function by fighting opportunistic infections. It binds to NUPR1, suggesting regulation of the apoptotic process. Prothymosin alpha Protein, Rat (P.pastoris, His) is the recombinant rat-derived Prothymosin alpha protein, expressed by P. pastoris , with N-His labeled tag.
- Species: Rat
- Source: P. pastoris
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Thymosin alpha protein is a multifunctional player that may mediate immune function by fighting opportunistic infections. It binds to NUPR1, suggesting regulation of the apoptotic process. Prothymosin alpha Protein, Rat (P.pastoris, His) is the recombinant rat-derived Prothymosin alpha protein, expressed by P. pastoris , with N-His labeled tag.
Background
Prothymosin alpha, a multifunctional protein, potentially plays a pivotal role in mediating immune function by conferring resistance against specific opportunistic infections. Through its intricate molecular interactions, prothymosin alpha engages with NUPR1, suggesting its involvement in the regulation of apoptotic processes. The multifaceted functions of prothymosin alpha underscore its significance in orchestrating immune responses and cellular homeostasis. Further elucidation of its molecular interactions and regulatory roles can provide valuable insights into the complex mechanisms through which prothymosin alpha contributes to immune function and apoptotic regulation in cellular contexts.
Publications (1)
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Journal Impact Factor
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Most Recent
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Sci Immunol
PTMA safeguards mitochondrial integrity to sustain metabolic function and antitumor activity of CD8 T cells. [Abstract]2026 Jan 23;11(115):eadz7275. PMID: 41544148
Technical Parameters
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Species Rat
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Source P. pastoris
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Tag N-6*His
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Accession
P06302 (S2-D112)
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Gene ID100359583 [NCBI]
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Molecular Construction
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N-term
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His
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ProTα (S2-D112)
Accession # P06302 -
C-term
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Protein Length
Full Length of Prothymosin alpha, N-terminally processed Chain
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Synonyms
PTMA; Prothymosin Alpha Protein; Prev. TMSA; Prothymosin-I+/-; Gene Sequence 28; Prothymosin-Α; Prothymosin, Alpha (Gene Sequence 28); Prothymosin Alpha; Prothymosin, Alpha
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AA Sequence
SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVETKKQKKTDEDD
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Predicted Molecular Mass
14.3 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, 6% trehalose, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (235 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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