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Prothymosin alpha Protein, Rat (P.pastoris, His)

Cat. No.: HY-P71776
Handling Instructions

Thymosin alpha protein is a multifunctional player that may mediate immune function by fighting opportunistic infections. It binds to NUPR1, suggesting regulation of the apoptotic process. Prothymosin alpha Protein, Rat (P.pastoris, His) is the recombinant rat-derived Prothymosin alpha protein, expressed by P. pastoris , with N-His labeled tag. The total length of Prothymosin alpha Protein, Rat (P.pastoris, His) is 111 a.a., with molecular weight of ~14.3 kDa.

For research use only. We do not sell to patients.

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Description

Thymosin alpha protein is a multifunctional player that may mediate immune function by fighting opportunistic infections. It binds to NUPR1, suggesting regulation of the apoptotic process. Prothymosin alpha Protein, Rat (P.pastoris, His) is the recombinant rat-derived Prothymosin alpha protein, expressed by P. pastoris , with N-His labeled tag. The total length of Prothymosin alpha Protein, Rat (P.pastoris, His) is 111 a.a., with molecular weight of ~14.3 kDa.

Background

Prothymosin alpha, a multifunctional protein, potentially plays a pivotal role in mediating immune function by conferring resistance against specific opportunistic infections. Through its intricate molecular interactions, prothymosin alpha engages with NUPR1, suggesting its involvement in the regulation of apoptotic processes. The multifaceted functions of prothymosin alpha underscore its significance in orchestrating immune responses and cellular homeostasis. Further elucidation of its molecular interactions and regulatory roles can provide valuable insights into the complex mechanisms through which prothymosin alpha contributes to immune function and apoptotic regulation in cellular contexts.

Species

Rat

Source

P. pastoris

Tag

N-His

Accession

P06302 (2S-112D)

Gene ID

100359583  [NCBI]

Molecular Construction
N-term
His
ProTα (2S-112D)
Accession # P06302
C-term
Synonyms
Ptma; N-terminally processed
AA Sequence

SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVETKKQKKTDEDD

Molecular Weight

Approximately 14.3 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Prothymosin alpha Protein, Rat (P.pastoris, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Prothymosin alpha Protein, Rat (P.pastoris, His)
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HY-P71776
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