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  3. ROBO4 Protein, Mouse (453a.a, HEK293, His)

ROBO4 Protein, Mouse (453a.a, HEK293, His)

Cat. No.: HY-P78031
Handling Instructions

ROBO4 protein, as a receptor for Slit proteins (especially SLIT2), plays a key role in angiogenesis and blood vessel pattern formation. It mediates the inhibition of primary endothelial cell migration by Slit protein and actively maintains endothelial barrier organization and function. ROBO4 Protein, Mouse (453a.a, HEK293, His) is the recombinant mouse-derived ROBO4 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROBO4 Protein, Mouse (453a.a, HEK293, His) is 453 a.a., with molecular weight of 60-70 kDa.

For research use only. We do not sell to patients.

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Description

ROBO4 protein, as a receptor for Slit proteins (especially SLIT2), plays a key role in angiogenesis and blood vessel pattern formation. It mediates the inhibition of primary endothelial cell migration by Slit protein and actively maintains endothelial barrier organization and function. ROBO4 Protein, Mouse (453a.a, HEK293, His) is the recombinant mouse-derived ROBO4 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROBO4 Protein, Mouse (453a.a, HEK293, His) is 453 a.a., with molecular weight of 60-70 kDa.

Background

ROBO4 Protein functions as a receptor for Slit proteins, particularly SLIT2, and plays a crucial role in angiogenesis and vascular patterning. This receptor is implicated in mediating the inhibition of primary endothelial cell migration by Slit proteins. Additionally, ROBO4 is actively involved in maintaining the organization and functionality of the endothelial barrier. Through its interactions with SLIT2 and ENAH, ROBO4 contributes to intricate cellular processes, shedding light on its significance in vascular development and the regulation of endothelial cell behavior.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q8C310 (L28-W480)

Gene ID

74144  [NCBI]

Molecular Construction
N-term
ROBO4 (L28-W480)
Accession # Q8C310
His
C-term
Synonyms
ECSM4; MRB; FLJ20798; MGC133352; MGC133353; ROBO4
Molecular Weight

60-70 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

ROBO4 Protein, Mouse (453a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ROBO4 Protein, Mouse (453a.a, HEK293, His)
Cat. No.:
HY-P78031
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