RPS6KA6 Protein, Human (Active, sf9, GST)

RSK4 (ribosomal S6 kinase 4) is a serine/threonine protein kinase that is constitutively active and does not require the presence of growth factors to function. It is involved in cell signaling pathways related to cell growth arrest, especially those mediated by p53/TP53 proteins. RPS6KA6 Protein, Human (sf9, GST) is the recombinant human-derived RPS6KA6, expressed by Sf9 insect cells, with GST labeled tag.

RSK4 (Ribosomal S6 kinase 4) is a serine/threonine-protein kinase that exhibits constitutive activity and does not require the presence of growth factors to function. It is involved in cellular signaling pathways related to cell growth arrest, particularly those mediated by the p53/TP53 protein. RSK4 is thought to play a role in inhibiting cell growth during embryogenesis, suggesting its importance in regulating development processes. By understanding the function and regulation of RSK4, we can gain insights into the mechanisms underlying cell growth control and potential implications in embryonic development and related disorders.

Human

Sf9 insect cells

GST

Q9UK32 (M1-L745)

27330

Full Length

MLPFAPQDEPWDREMEVFSGGGASSGEVNGLKMVDEPMEEGEADSCHDEGVVKEIPITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHVVKGAMVATYSALTHKTFQPVLEPVAASSLAQRRSMKKRTSTGL

≥ 80%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.