RPS6KB2 Protein, Human (Active, sf9, GST)
RPS6KB2 Protein, Human (Inactive, sf9, His, GST) is the recombinant human-derived RPS6KB2, expressed by sf9 insect cells , with His, GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Biological Activity
Description
RPS6KB2 Protein, Human (Inactive, sf9, His, GST) is the recombinant human-derived RPS6KB2, expressed by sf9 insect cells , with His, GST labeled tag. ,
Background
RPS6KB2 is a kinase that specifically phosphorylates ribosomal protein S6. It appears to act downstream of mTOR signaling in response to growth factors and nutrients, promoting cell proliferation, cell growth, and cell cycle progression through an alternative pathway regulated by MEAK7.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-GST
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Accession
AAH00094.3 (M1-R482)
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Gene ID6199
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Molecular Construction
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N-term
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GST
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RPS6KB2 (M1-R482)
Accession # AAH00094.3 -
C-term
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Protein Length
Full Length
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Synonyms
RPS6KB2; S6K-Beta; Ribosomal Protein S6 Kinase B2; P70 S6KB; STK14B; P70S6K2; P70-BETA; S6K2; P70S6Kb; SRK; S6Kbeta; Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2; S6KB; Ribosomal Protein S6 Kinase, 70kD, Polypeptide 2; KLS; Serine/Threonine-Protein K
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AA Sequence
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR
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Molecular Weight
Approximately 85 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)