SAE2 Protein, Human
SAE2 Protein, Human is the recombinant human-derived SAE2, expressed by E. coli , with tag Free labeled tag. ,
- Species: Human
- Source: E. coli
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Biological Activity
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Product Properties
- Documentation
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Biological Activity
SAE2 Protein, Human is the recombinant human-derived SAE2, expressed by E. coli , with tag Free labeled tag. ,
SAE2 is a heterodimer that functions as an E1 ligase for SUMO1, SUMO2, SUMO3, and likely SUMO4. It mediates the ATP-dependent activation of SUMO proteins, followed by the formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Technical Parameters
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Species Human
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Source E. coli
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Tag Tag Free
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Accession
Q9UBT2-1 (M1-D640)
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Gene ID10054
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Protein Length
Full Length of Isoform-1
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Synonyms
SAE2; UBLE1B
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AA Sequence
MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDAPEKVGPKQAEDAAKSITNGSDDGAQPSTSTAQEQDDVLIVDSDEEDSSNNADVSEEERSRKRKLDEKENLSAKRSRIEQKEELDDVIALD
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Predicted Molecular Mass
71.4 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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