Semaphorin-3A/SEMA3A Protein, Mouse (HEK293, His, solution)
Based on 1 Customer Validation
Semaphorin-3A/SEMA3A Protein guides growth cones and is implicated in sensory projection patterning, selectively repelling axons that terminate dorsally.It contributes to olfactory system development and neuronal control of puberty.SEMA3A interacts with PXND1, although the exact nature of this interaction is unspecified. Semaphorin-3A/SEMA3A Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Semaphorin-3A/SEMA3A protein, expressed by HEK293 , with N-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Semaphorin-3A/SEMA3A Protein guides growth cones and is implicated in sensory projection patterning, selectively repelling axons that terminate dorsally.It contributes to olfactory system development and neuronal control of puberty.SEMA3A interacts with PXND1, although the exact nature of this interaction is unspecified. Semaphorin-3A/SEMA3A Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Semaphorin-3A/SEMA3A protein, expressed by HEK293 , with N-His labeled tag.
Background
The Semaphorin-3A/SEMA3A protein plays a crucial role in guiding growth cones. It is believed to participate in patterning sensory projections by selectively repelling axons that typically terminate dorsally. SEMA3A is also involved in the development of the olfactory system and contributes to neuronal control of puberty. Additionally, it interacts with PXND1, although the exact nature of this interaction is not specified.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag N-8*His
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Accession
O08665 (Y21-V772)
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Gene ID20346
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Molecular Construction
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N-term
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8*His
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SEMA3A (Y21-V772)
Accession # O08665 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
SEMA3A; Sema III; Prev. SEMAD; Semaphorin D; Hsema-I; Semaphorin L; Coll-1; Collapsin 1; SEMA1; Hsema-III; SemD; SEMAIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SEMAL; Semaphorin-3A;
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Predicted Molecular Mass
86.6 kDa
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Molecular Weight
Approximately 65-70 kDa, based on SDS-PAGE under reducing conditions, due to furin cleavage.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of PBS, pH 7.4 and 200 mM L-Argine.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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