CARKL Protein, Human (HEK293, His)
CARKL Protein acts as a modulator of macrophage activation, controlling glucose metabolism and influencing the functional phenotype of macrophages. Its regulatory role underscores its significance in shaping cellular processes and contributes to understanding the molecular mechanisms governing immune responses and cellular homeostasis. CARKL Protein, Human (HEK293, His) is the recombinant human-derived CARKL protein, expressed by HEK293 , with C-6*His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
CARKL Protein acts as a modulator of macrophage activation, controlling glucose metabolism and influencing the functional phenotype of macrophages. Its regulatory role underscores its significance in shaping cellular processes and contributes to understanding the molecular mechanisms governing immune responses and cellular homeostasis. CARKL Protein, Human (HEK293, His) is the recombinant human-derived CARKL protein, expressed by HEK293 , with C-6*His labeled tag.
Background
CARKL Protein functions as a modulator of macrophage activation, exerting control over glucose metabolism. Its regulatory role in the intricate interplay of cellular processes underscores its significance in orchestrating the activation state of macrophages. By influencing glucose metabolism, CARKL likely plays a pivotal role in shaping the functional phenotype of macrophages, contributing to the broader understanding of the molecular mechanisms governing immune responses and cellular homeostasis.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-6*His
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Accession
Q9UHJ6 (M1-S478)
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Molecular Construction
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N-term
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CARKL (M1-S478)
Accession # Q9UHJ6 -
6*His
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C-term
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Protein Length
Full Length
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Synonyms
SHPK; SHK; Prev. CARKL; Carbohydrate Kinase-Like; Sedoheptulokinase; Carbohydrate Kinase-Like Protein
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AA Sequence
MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQEWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES
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Predicted Molecular Mass
52.5 kDa
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Molecular Weight
Approximately 53 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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