SLC14A1 Protein, Human (sf9, His, MBP, FLAG)
SLC14A1 Protein plays a pivotal role in cellular processes, mediating urea transport across erythrocyte and renal inner medullary collecting duct membranes. It is crucial for the urinary concentrating mechanism and regulates water transport in erythrocytes. With a dual role in urea transport, SLC14A1 maintains cellular osmotic balance and contributes to physiological processes associated with urinary concentration, highlighting its significance. SLC14A1 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC14A1 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
SLC14A1 Protein plays a pivotal role in cellular processes, mediating urea transport across erythrocyte and renal inner medullary collecting duct membranes. It is crucial for the urinary concentrating mechanism and regulates water transport in erythrocytes. With a dual role in urea transport, SLC14A1 maintains cellular osmotic balance and contributes to physiological processes associated with urinary concentration, highlighting its significance. SLC14A1 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC14A1 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
Background
SLC14A1 Protein assumes a pivotal role in cellular processes by mediating the transport of urea across the cell membrane of erythrocytes, driven by a concentration gradient. Additionally, SLC14A1 plays a crucial role in the urinary concentrating mechanism by mediating the transport of urea across the cell membrane of the renal inner medullary collecting duct. This function is integral to the regulation of water transport in erythrocytes. The protein's dual role in urea transport underscores its significance in maintaining cellular osmotic balance and contributing to the physiological processes associated with urinary concentration.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-MBP;C-Flag;N-8*His
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Accession
Q13336 (E2-L389)
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Gene ID6563
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Molecular Construction
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N-term
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8*His-MBP
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SLC14A1 (E2-L389)
Accession # Q13336 -
Flag
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C-term
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Protein Length
Full Length
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Synonyms
SLC14A1; Solute Carrier Family 14 (Urea Transporter), Member 1; Prev. JK; Urea Transporter JK Glycoprotein; RACH1; Mutant KIDD Blood Group Antigen; Urea Transporter, Erythrocyte; Truncated Kidd Blood Group; Urea Transporter 1; Urea Transporter-B1; HsT1341
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AA Sequence
EDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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