SLC14A1 Protein, Human (sf9, His, MBP, FLAG)

SLC14A1 Protein plays a pivotal role in cellular processes, mediating urea transport across erythrocyte and renal inner medullary collecting duct membranes. It is crucial for the urinary concentrating mechanism and regulates water transport in erythrocytes. With a dual role in urea transport, SLC14A1 maintains cellular osmotic balance and contributes to physiological processes associated with urinary concentration, highlighting its significance. SLC14A1 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC14A1 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.

SLC14A1 Protein assumes a pivotal role in cellular processes by mediating the transport of urea across the cell membrane of erythrocytes, driven by a concentration gradient. Additionally, SLC14A1 plays a crucial role in the urinary concentrating mechanism by mediating the transport of urea across the cell membrane of the renal inner medullary collecting duct. This function is integral to the regulation of water transport in erythrocytes. The protein's dual role in urea transport underscores its significance in maintaining cellular osmotic balance and contributing to the physiological processes associated with urinary concentration.

Human

Sf9 insect cells

N-MBP;C-Flag;N-8*His

Q13336 (E2-L389)

6563

Partial

EDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.