SLC30A3 Protein, Human (sf9, His, MBP, FLAG)
The SLC30A3 protein is a possible proton-coupled zinc antiporter that mediates cellular zinc homeostasis in the brain. It promotes zinc import into synaptic vesicles and regulates intracellular zinc levels, which are critical for neuronal processes. SLC30A3 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC30A3 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
The SLC30A3 protein is a possible proton-coupled zinc antiporter that mediates cellular zinc homeostasis in the brain. It promotes zinc import into synaptic vesicles and regulates intracellular zinc levels, which are critical for neuronal processes. SLC30A3 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC30A3 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.
Background
The SLC30A3 protein is identified as a probable proton-coupled zinc ion antiporter, playing a pivotal role in the cellular zinc ion homeostasis within the brain. Functioning as a mediator, it facilitates the import of zinc from the cytoplasm into synaptic vesicles, contributing to the regulation of intracellular zinc levels. This proton-coupled zinc ion antiporter activity suggests its involvement in maintaining the delicate balance of zinc ions, crucial for various cellular processes in neuronal environments. Further exploration of the precise mechanisms and regulatory functions of SLC30A3 in synaptic zinc transport will provide valuable insights into its role in neurophysiology and cellular homeostasis within the brain.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-MBP;C-Flag;N-8*His
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Accession
Q99726 (E2-A388)
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Gene ID7781
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Molecular Construction
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N-term
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8*His-MBP
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SLC30A3 (E2-A388)
Accession # Q99726 -
Flag
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C-term
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Protein Length
Full Length
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Synonyms
SLC30A3; Solute Carrier Family 30 (Zinc Transporter), Member 3; Prev. ZNT3; Putative Proton-Coupled Zinc Antiporter SLC30A3; Probable Proton-Coupled Zinc Antiporter SLC30A3; Zinc Transporter ZnT-3; Zinc Transporter 3; Solute Carrier Family 30 Member 3; Zn
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AA Sequence
EPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAACAVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVLGDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQA
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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