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SLC30A3 Protein, Human (Sf9, His, MBP, FLAG)

Cat. No.: HY-P702015
Handling Instructions

The SLC30A3 protein is a possible proton-coupled zinc antiporter that mediates cellular zinc homeostasis in the brain. It promotes zinc import into synaptic vesicles and regulates intracellular zinc levels, which are critical for neuronal processes. SLC30A3 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC30A3 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC30A3 Protein, Human (Sf9, His, MBP, FLAG) is 387 a.a., .

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Description

The SLC30A3 protein is a possible proton-coupled zinc antiporter that mediates cellular zinc homeostasis in the brain. It promotes zinc import into synaptic vesicles and regulates intracellular zinc levels, which are critical for neuronal processes. SLC30A3 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC30A3 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC30A3 Protein, Human (Sf9, His, MBP, FLAG) is 387 a.a., .

Background

The SLC30A3 protein is identified as a probable proton-coupled zinc ion antiporter, playing a pivotal role in the cellular zinc ion homeostasis within the brain. Functioning as a mediator, it facilitates the import of zinc from the cytoplasm into synaptic vesicles, contributing to the regulation of intracellular zinc levels. This proton-coupled zinc ion antiporter activity suggests its involvement in maintaining the delicate balance of zinc ions, crucial for various cellular processes in neuronal environments. Further exploration of the precise mechanisms and regulatory functions of SLC30A3 in synaptic zinc transport will provide valuable insights into its role in neurophysiology and cellular homeostasis within the brain.

Species

Human

Source

Sf9 insect cells

Tag

N-MBP;C-Flag;N-8*His

Accession

Q99726 (E2-A388)

Gene ID

7781

Molecular Construction
N-term
8*His-MBP
SLC30A3 (E2-A388)
Accession # Q99726
Flag
C-term
Synonyms
SLC30A3; Zinc transporter 3; ZnT-3; Solute carrier family 30 member 3
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SLC30A3 Protein, Human (Sf9, His, MBP, FLAG) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SLC30A3 Protein, Human (Sf9, His, MBP, FLAG)
Cat. No.:
HY-P702015
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