SLC38A2 Protein, Human (HEK293, His, MBP, Flag)
SLC38A2 Protein, Human (HEK293, His, MBP, Flag) is the recombinant human-derived SLC38A2, expressed by HEK293 , with His, MBP, Flag labeled tag. ,
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
SLC38A2 Protein, Human (HEK293, His, MBP, Flag) is the recombinant human-derived SLC38A2, expressed by HEK293 , with His, MBP, Flag labeled tag. ,
Background
SLC38A2 is a symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient, and involves a 1:1 stoichiometry of neutral amino acids and sodium ions. It may function in amino acid transport at the blood-brain barrier and in supplying maternal nutrients to the fetus through the placenta (by similar). Additionally, SLC38A2 maintains a key glutamine/glutamate metabolic balance, supporting retrograde signaling via dendritic release of the neurotransmitter glutamate (by similar). In differentiating osteoblasts, it transports L-proline for efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (by similar).
Technical Parameters
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Species Human
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Source HEK293
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Tag His;MBP;Flag
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Accession
Q96QD8-1 (K2-H506)
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Gene ID54407
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Protein Length
Full Length of Isoform-1
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Synonyms
SLC38A2; Amino Acid Transporter A2; Solute Carrier Family 38 Member 2; System A Transporter 1; SNAT2; KIAA1382; SAT2; Sodium-Coupled Neutral Amino Acid Transporter 2; ATA2; Protein 40-9-1; Sodium-Coupled Neutral Amino Acid Symporter 2; Solute Carrier Fami
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AA Sequence
KKAEMGRFSISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAPGGGH
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Predicted Molecular Mass
99.8 kDa
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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