SLITRK6 Protein, Human (Biotinylated, HEK293, His-Avi)

The SLITRK6 protein is a key regulator that coordinates neurite growth, which is critical for normal hearing and vision, affecting neuronal development and intercellular communication. Its importance in sensory function emphasizes its important role in the molecular mechanisms of sensory perception. SLITRK6, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SLITRK6 protein, expressed by HEK293, with N-Avi labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

The SLITRK6 protein is a key regulator that coordinates neurite growth, which is critical for normal hearing and vision, affecting neuronal development and intercellular communication. Its importance in sensory function emphasizes its important role in the molecular mechanisms of sensory perception. SLITRK6, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SLITRK6 protein, expressed by HEK293, with N-Avi labeled tag.

Background

SLITRK6 emerges as a key regulator in the intricate orchestration of neurite outgrowth, playing a crucial role in maintaining normal hearing and vision. This protein's influence extends to the intricate processes involved in neuronal development, particularly in the growth of neurites, which are essential structures for intercellular communication. The significance of SLITRK6 in sensory functions, such as hearing and vision, emphasizes its importance in the intricate network of molecular mechanisms that underlie sensory perception. As a regulator of neurite outgrowth, SLITRK6 contributes to the establishment and maintenance of neuronal connections critical for proper sensory processing, shedding light on its vital role in neural development and sensory function.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-Avi;C-His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • SLITRK6 (S27-S608)
      Accession # Q9H5Y7
    • His-Avi
    • C-term
  • Protein Length

    Extracellular Domain

  • Conjugation

    Biotin

  • Synonyms

    SLITRK6; SLIT And NTRK-Like Family, Member 6; SLIT And NTRK Like Family Member 6; Slit And Trk Like Gene 6; SLIT And NTRK-Like Protein 6; 4832410J21Rik; FLJ22774; DFNMYP

  • AA Sequence

    SRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVVCNSPPFFKGSILSRLKKESICPTPPVYEEHEDPSGSLHLAATSSINDSRMSTKTTSILKLPTKAPGLIPYITKPSTQLPGPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQTSYLMVTTPATTTNTADTILRSLTDAVPLS

  • Predicted Molecular Mass

    68.4 kDa

  • Molecular Weight

    Approximately 80-90 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 90%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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