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  3. TFF3 Protein, Canine (HEK293, His)

TFF3 Protein, Canine (HEK293, His)

Cat. No.: HY-P700527
Handling Instructions

TFF3 Protein intricately maintains and repairs the intestinal mucosa, acting as a motogen that promotes epithelial cell mobility during healing. Existing as a monomer, TFF3 can form homodimers through disulfide linkages, suggesting a role in mediating crucial interactions. Its involvement in mucosal repair underscores TFF3's significance in dynamic processes that preserve the integrity and functionality of the intestinal lining. TFF3 Protein, Canine (HEK293, His) is the recombinant canine-derived TFF3 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of TFF3 Protein, Canine (HEK293, His) is 57 a.a., with molecular weight of 9.2 kDa.

For research use only. We do not sell to patients.

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Description

TFF3 Protein intricately maintains and repairs the intestinal mucosa, acting as a motogen that promotes epithelial cell mobility during healing. Existing as a monomer, TFF3 can form homodimers through disulfide linkages, suggesting a role in mediating crucial interactions. Its involvement in mucosal repair underscores TFF3's significance in dynamic processes that preserve the integrity and functionality of the intestinal lining. TFF3 Protein, Canine (HEK293, His) is the recombinant canine-derived TFF3 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of TFF3 Protein, Canine (HEK293, His) is 57 a.a., with molecular weight of 9.2 kDa.

Background

The TFF3 Protein is intricately involved in the maintenance and repair of the intestinal mucosa, playing a pivotal role in promoting the mobility of epithelial cells during healing processes, acting as a motogen. The protein exists as a monomer and can form homodimers through disulfide linkages. This dimeric structure underscores its potential role in mediating interactions crucial for its functional activities. TFF3's participation in mucosal repair highlights its significance in contributing to the dynamic processes that maintain the integrity and functionality of the intestinal lining.

Species

Canine

Source

HEK293

Tag

C-10*His

Accession

Q863B4 (Y24-F80)

Gene ID

403488  [NCBI]

Molecular Construction
N-term
TFF3 (Y24-F80)
Accession # Q863B4
10*His
C-term
Synonyms
TFF3; trefoil factor 3 (intestinal); ITF; Polypeptide P1.B; TFI; HITF; trefoil factor 3, HITF, human intestinal trefoil factor; OTTHUMP00000109349; P1B; trefoil factor 3; hITF; hP1.B; Intestinal trefoil factor
AA Sequence

YQGLATNLCEVPPKDRVDCGYPEITSEQCVNRGCCFDSSIHGVPWCFKPLQDTECRF

Molecular Weight

9.2 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

TFF3 Protein, Canine (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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TFF3 Protein, Canine (HEK293, His)
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HY-P700527
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