TROP-2 Protein, Mouse (Biotinylated, HEK293, His-Avi)
The TROP-2 protein functions as a growth factor receptor and has been shown to play a critical role in mediating cellular responses associated with growth regulation. Its involvement indicates that it plays a crucial role in signal transduction during cell growth. TROP-2, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived TROP-2 protein, expressed by HEK293, with N-Avi labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The TROP-2 protein functions as a growth factor receptor and has been shown to play a critical role in mediating cellular responses associated with growth regulation. Its involvement indicates that it plays a crucial role in signal transduction during cell growth. TROP-2, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived TROP-2 protein, expressed by HEK293, with N-Avi labeled tag.
Background
The TROP-2 protein appears to function as a growth factor receptor, suggesting a key role in mediating cellular responses associated with growth regulation. Its involvement in this capacity indicates that TROP-2 may play a crucial role in transducing signals that contribute to cellular growth processes. Further exploration of the specific signaling pathways and downstream effects mediated by TROP-2 as a growth factor receptor could provide valuable insights into its functional significance and potential implications in cellular development and homeostasis.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-Avi;C-His
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Accession
Q8BGV3 (Q25-G270)
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Gene ID56753
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Molecular Construction
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N-term
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TROP-2 (Q25-G270)
Accession # Q8BGV3 -
His-Avi
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C-term
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Protein Length
Extracellular Domain
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Conjugation
Biotin
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Synonyms
TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal Tumor-Associated Antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; Tumor-Associated Calcium Signal Transducer 2;
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AA Sequence
QSNCTCPTNKMTVCDTNGPGGVCQCRAMGSQVLVDCSTLTSKCLLLKARMSARKSGRSLVMPSEHAILDNDGLYDPECDDKGRFKARQCNQTSVCWCVNSVGVRRTDKGDQSLRCDEVVRTHHILIELRHRPTDRAFNHSDLDSELRRLFQERYKLHPSFLSAVHYEEPTIQIELRQNASQKGLRDVDIADAAYYFERDIKGESLFMGRRGLDVQVRGEPLHVERTLIYYLDEKPPQFSMKRLTAG
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Predicted Molecular Mass
31.6 kDa
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Molecular Weight
Approximately 42-52 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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