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Cat. No.: HY-168452

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RNase L ligand 1

RNase L ligand 1 (Compound F1-COOH) is the ligand for RNase L that can be used for synthesis of F1-RIBOTAC (HY-171148).

For research use only. We do not sell to patients.

Formula: C₂₁H₂₁Cl₂NO₃
Molecular Weight:406.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

RNase L ligand 1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

RNase L ligand 1 (Compound F1-COOH) is the ligand for RNase L that can be used for synthesis of F1-RIBOTAC (HY-171148)^[1].

IC₅₀ & Target

RNASE L

All DNA/RNA Synthesis Isoforms :

Chemical Information

Molecular Weight 406.30
Formula C₂₁H₂₁Cl₂NO₃
SMILES

OC(CCC(N([C@@H]1C2=CC=CC=C2[C@H](C3=CC(Cl)=C(C=C3)Cl)CC1)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tong Y, et al., Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA. J Am Chem Soc. 2022 Jul 6;144(26):11620-11625. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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