2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. (S)-SKBG-1

(S)-SKBG-1 is an inactive and covalent NONO ligand, used for assay control..

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(S)-SKBG-1

(S)-SKBG-1 Chemical Structure

CAS No. : 2955618-24-1

Size Prix Stock Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg   Obtenir un devis  
100 mg   Obtenir un devis  

* Veuillez sélectionner la quantité avant d'ajouter des articles.

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Other Forms of (S)-SKBG-1:

(S)-SKBG-1 Related Antibodies

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  • Activité biologique

  • Pureté et documentation

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Description

(S)-SKBG-1 is an inactive and covalent NONO ligand, used for assay control..

IC50 & Target

NONO[1]
Masse moléculaire

495.98

Formule

C22H26ClN3O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(N1[C@@H](CN(CC1)C(CCl)=O)C(NCC2=CC=C(C=C2)OC)=O)(C3=CC=C(C=C3)OC)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvant et solubilité
In Vitro: 

DMSO : 100 mg/mL (201.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0162 mL 10.0811 mL 20.1621 mL
5 mM 0.4032 mL 2.0162 mL 4.0324 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0162 mL 10.0811 mL 20.1621 mL 50.4053 mL
5 mM 0.4032 mL 2.0162 mL 4.0324 mL 10.0811 mL
10 mM 0.2016 mL 1.0081 mL 2.0162 mL 5.0405 mL
15 mM 0.1344 mL 0.6721 mL 1.3441 mL 3.3604 mL
20 mM 0.1008 mL 0.5041 mL 1.0081 mL 2.5203 mL
25 mM 0.0806 mL 0.4032 mL 0.8065 mL 2.0162 mL
30 mM 0.0672 mL 0.3360 mL 0.6721 mL 1.6802 mL
40 mM 0.0504 mL 0.2520 mL 0.5041 mL 1.2601 mL
50 mM 0.0403 mL 0.2016 mL 0.4032 mL 1.0081 mL
60 mM 0.0336 mL 0.1680 mL 0.3360 mL 0.8401 mL
80 mM 0.0252 mL 0.1260 mL 0.2520 mL 0.6301 mL
100 mM 0.0202 mL 0.1008 mL 0.2016 mL 0.5041 mL
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(S)-SKBG-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-SKBG-12955618-24-1Ligands for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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HY-153918A
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