SARS-CoV-2 3CLpro-IN-6
SARS-CoV-2 3CLpro-IN-6 is a reversible covalent inhibitor of SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro-IN-6 has potent inhibitory activity for SARS-CoV-2 3CLpro with an IC50 value of 4.9 μM. SARS-CoV-2 3CLpro-IN-6 can be used for the research of coronavirus disease 2019 (COVID-19).
For research use only. We do not sell to patients.
- CAS No.: 302821-53-0
- Formula: C22H15NO7
- Molecular Weight:405.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 4.9 μM (SARS-CoV-2 3CLpro)[1]
SARS-CoV-2 3CLpro-IN-6 (Compound 13) (0-100 μM) has potent inhibitory activity for SARS-CoV-2 3CLpro with IC50 value of 4.9 μM[1].
SARS-CoV-2 3CLpro-IN-6 (5, 10 μM) has typical covalent inhibition behavior with time-dependent activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 302821-53-0
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Molecular Weight 405.36
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Formula C22H15NO7
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SMILES
COC(C(/C(C(C1=CC=CC=C1)=O)=C\C2=CC=C(O2)C3=C(C=CC=C3)[N+]([O-])=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)