SARS-CoV-2 Mpro-IN-43
SARS-CoV-2 Mpro-IN-43 (Compound 1) is a coronavirus main protease (Mpro) inhibitor (IC50: 72 μM). SARS-CoV-2 Mpro-IN-43 interacts with key residues in the active site of Mpro via non-covalent binding, exerting its anti-coronavirus effect. SARS-CoV-2 Mpro-IN-43 exhibits moderate to low cytotoxicity, with CC50 values of 13.24, 41.02, and 42.26 µM in HaCaT, HEK293T, and HepG2 cells, respectively. SARS-CoV-2 Mpro-IN-43 can be used in anti-SARS-CoV-2 research.
For research use only. We do not sell to patients.
- Formula: C32H41F3N2O4S2
- Molecular Weight:638.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 638.80
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Formula C32H41F3N2O4S2
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SMILES
S=C(N1CCN(CC2=CC(F)=C(F)C=C2F)CC1)S[C@H](C3=CCOC3=O)C[C@@H]4C(CC[C@]5([H])[C@](C)(CO)[C@H](O)CC[C@@]45C)=C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)