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Cat. No.: HY-101105AR

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SB-224289 hydrochloride (Standard)

Name: SB-224289 hydrochloride (Standard)
Brand: MedChemExpress
SKU: HY-101105AR
Availability: PreOrder

(Synonyms: SB-224289A (Standard))

SB-224289 (hydrochloride) (Standard) is the analytical standard of SB-224289 (hydrochloride) (HY-101105A). This product is intended for research and analytical applications. SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.

For research use only. We do not sell to patients.

CAS No.: 180084-26-8
Formula: C₃₂H₃₃ClN₄O₃
Molecular Weight:557.08

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SB-224289 hydrochloride (Standard) Chemical Structure

CAS No.: 180084-26-8

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 180084-26-8
Molecular Weight 557.08
Formula C₃₂H₃₃ClN₄O₃
SMILES

O=C(C1=CC=C(C2=CC=C(C3=NOC(C)=N3)C=C2C)C=C1)N4CCC5=C4C=C6C(OCC67CCN(C)CC7)=C5.Cl
Synonyms

SB-224289A (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS One. 2016 May 16;11(5):e0154932. [Content Brief]

[2]. Hoplight BJ, et al. The effects of SB 224289 on anxiety and cocaine-related behaviors in a novel object task. Physiol Behav. 2005 Apr 13;84(5):707-14. Epub 2005 Apr 13. [Content Brief]

[3]. Gaster LM, et al. The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo. Ann N Y Acad Sci. 1998 Dec 15;861:270-1. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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