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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
APAP
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "APAP" in MCE Product Catalog:
Cat. No.: HY-183995
Research Areas:
SH-26 is a PHD1 PROTAC degrader with DC50s of 1.06 μM, 4.16 μM and 4.91 μM in MDA-MB-231, HepG2 and HEK-293T cells, respectively. SH-26 recruits CRBN to induce PHD1 degradation via the ubiquitin-proteasome system. SH-26 attenuates APAP (HY-66005)-triggered ROS accumulation, mitochondrial dysfunction, and NLRP3 inflammasome activation. SH-26 can be used for the research of acute liver injury .
Cat. No.: HY-D3403
CAS No.: 3121511-19-8
Target:
Research Areas:
LHA930 is a fluorescent probe for in vivo detection of early-stage ferroptosis. By introducing a 4-phenyl-3-methylbut-2-enyl reactive group responsive to lipid hydrogen abstraction, LHA930 exhibits fluorescence turn-on upon the action of oxidative radicals associated with lipid peroxidation, enabling detection of lipid peroxidation during the early stage of ferroptosis. The detection wavelength of LHA930 is Ex/Em = 860/930 nm. LHA930 can be used for near-infrared fluorescence imaging studies of ferroptosis in APAP-induced mouse liver injury models .
Cat. No.: HY-P74590
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RYBP; RING1 And YY1-Binding Protein; RING1 And YY1 Binding Protein; Ring1 Interactor RYBP; YEAF1; DED-Associated Factor; DEDAF; APAP-1; Death Effector Domain-Associated Factor; RING1 And YY1 Binding Protein, Isoform CRA_b; Apoptin-Associating Protein 1; Y
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
