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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
129 Results for "
Acinetobacter
" in MedChemExpress (MCE) Product Catalog:
Products (129)
129 Results for "Acinetobacter" in MCE Product Catalog:
Cat. No.: HY-123515
CAS No.: 39868-96-7
Research Areas:
Clorobiocin is an antibacterial agent with an IC50 of 0.21 μM against the B subunit of E. coli DNA gyrase. Clorobiocin targets the mLaC protein of Gram-negative bacteria. Clorobiocin potently inhibits bacterial DNA replication. Clorobiocin can be used in studies on Gram-negative bacterial infections, such as Acinetobacter baumannii and E. coli infections .
Cat. No.: HY-B0117S
CAS No.: 2699607-86-6
Synonyms: GAR-936-d9
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2,4-D Butyl ester is a phenoxyacetic acid herbicide used to control woody broadleaf weeds. 2,4-D Butyl ester shows high toxicity to fish and aquatic invertebrates. In animals, 2,4-D Butyl ester hydrolyzes to produce n-butanol, which further induces neurobehavioral toxicity such as ataxia in rats .
Cat. No.: HY-128780
CAS No.: 2407717-17-1
Synonyms: SPR206
Upleganan (SPR206), a polymyxin analogue, and shows antibiotic activity against multidrug resistant Gram-negative pathogen. The MIC values of Upleganan against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. DS86760016 inhibits LeuRS enzymes from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, with IC50s of 0.38, 0.62, and 0.16 μM, respectively .
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Cat. No.: HY-B0334AS
CAS No.: 1322625-44-4
Cat. No.: HY-B0334AR
CAS No.: 69388-84-7
Synonyms: CP45899 sodium (Standard)
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Sulbactam (sodium) (Standard) is the analytical standard of Sulbactam (sodium). This product is intended for research and analytical applications. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .
Cat. No.: HY-150063
CAS No.: 99330-28-6
Research Areas:
Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain .
Cat. No.: HY-147349A
CAS No.: 2410688-60-5
Synonyms: ANT3310
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Pilabactam (ANT3310) is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). Pilabactam potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). Pilabactam can be used in the research of bacterial infection .
Cat. No.: HY-147429A
Synonyms: Abx MCP TFA; RG6006 TFA
Zosurabalpin (Abx MCP; RG6006) TFA is a lipopolysaccharide (LPS) transport inhibitor that targets the LptB2FGC complex. Zosurabalpin TFA blocks the transport of LPS from the inner membrane to the outer membrane, leading to intracellular toxic accumulation of LPS and bacterial death. Zosurabalpin TFA exhibits potent antibacterial activity against carbapenem-resistant Acinetobacter baumannii (CRAB) and shows in vivo efficacy in mouse infection models. Zosurabalpin TFA can be used for research on CRAB infections, including pneumonia and sepsis .
Cat. No.: HY-129805
CAS No.: 119068-46-1
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BO 1341 is a PBPs inhibitor and an antipseudomonal semisynthetic cephalosporin, which belongs to the class of Antibiotic. BO 1341 exhibits antibacterial activity against most Gram-negative bacteria, such as Pseudomonas aeruginosa (MIC90: 1.56 μg/mL), Pseudomonas maltophilia (MIC50: 1.56 μg/mL), and Acinetobacter calcoaceticus (MIC90: 3.13 μg/mL) . BO 1341 can be used in the research of infectious diseases .
Cat. No.: HY-B0334AS1
CAS No.: 948027-82-5
Synonyms: CP45899-d2 sodium
Cat. No.: HY-B0334S
Synonyms: CP45899-d3
Cat. No.: HY-171112
CAS No.: 2380240-20-8
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KSP-1007 is a bicyclic boronate-based broad-spectrum β-lactamase inhibitor. KSP-1007 can effectively inhibit class A, B, C and D β-lactamases, including serine-type, metallo-type (such as NDM, VIM, IMP) and Acinetobacter baumannii OXA-type enzymes. KSP-1007 can enhance the antibacterial activity of Meropenem (HY-13678), reduce its MIC value, and be effective against carbapenemase-producing Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa. KSP-1007 can be used for the research of bacterial infection .
Cat. No.: HY-W127616A
CAS No.: 915-05-9
Synonyms: Sitosteryl acetate, 95%
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Arachidonyl alcohol is a long-chain primary fatty alcohol. Arachidonyl alcohol is used as a substrate for the production of several ether lipids possessing beneficial functions .
Cat. No.: HY-B0117B
CAS No.: 1135871-27-0
Synonyms: GAR-936 mesylate
Target:
Tigecycline mesylate (GAR-936 mesylate) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL . MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively .
Cat. No.: HY-160762
CAS No.: 524681-90-1
IMB-H4 is an antibacterial agent and BamA binder. IMB-H4 disrupts BamA-BamD interaction by binding to BamA. IMB-H4 shows growth inhibition to Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
