2. Others Metabolic Enzyme/Protease
  3. Environmental Pollutants Herbicide
  4. 2,4-D Butyl ester

2,4-D Butyl ester is a phenoxyacetic acid herbicide used to control woody broadleaf weeds. 2,4-D Butyl ester shows high toxicity to fish and aquatic invertebrates. In animals, 2,4-D Butyl ester hydrolyzes to produce n-butanol, which further induces neurobehavioral toxicity such as ataxia in rats.

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2,4-D Butyl ester

2,4-D Butyl ester Chemical Structure

CAS No. : 94-80-4

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Other Forms of 2,4-D Butyl ester:

2,4-D Butyl ester Related Antibodies

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Description

2,4-D Butyl ester is a phenoxyacetic acid herbicide used to control woody broadleaf weeds. 2,4-D Butyl ester shows high toxicity to fish and aquatic invertebrates. In animals, 2,4-D Butyl ester hydrolyzes to produce n-butanol, which further induces neurobehavioral toxicity such as ataxia in rats[1][2].

In Vitro

2,4-D Butyl ester (300 mg/L; 24 h) serves as the sole carbon source to support the optimal growth of Acinetobacter strain ZX02 in MSM medium at 29 °C and pH 7.0[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2,4-D Butyl ester Related Antibodies
In Vivo

2,4-D Butyl ester (150 mg/kg/day; s.c.; daily; 3-4 consecutive days) produces significant ataxia in male Wistar rats, as measured by landing foot splay increases of 118-124% of vehicle levels on days 3 and 4[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar (adult male, ~200 days old, 80-85% of free-feeding body weight)[2]
Dosage: 150 mg/kg/day
Administration: s.c.; daily; 3-4 consecutive days
Result: Increased landing foot splay to 118-124% of vehicle baseline levels on the third and fourth injection days.
Molecular Weight

277.14

Formula

C12H14Cl2O3
CAS No.
Appearance

Liquid (Density: 1.2639 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(OCCCC)COC1=CC=C(Cl)C=C1Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (360.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6083 mL 18.0414 mL 36.0828 mL
5 mM 0.7217 mL 3.6083 mL 7.2166 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.88%

SDS (597 KB)

COA (243 KB) HNMR (242 KB) LCMS (314 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6083 mL 18.0414 mL 36.0828 mL 90.2071 mL
5 mM 0.7217 mL 3.6083 mL 7.2166 mL 18.0414 mL
10 mM 0.3608 mL 1.8041 mL 3.6083 mL 9.0207 mL
15 mM 0.2406 mL 1.2028 mL 2.4055 mL 6.0138 mL
20 mM 0.1804 mL 0.9021 mL 1.8041 mL 4.5104 mL
25 mM 0.1443 mL 0.7217 mL 1.4433 mL 3.6083 mL
30 mM 0.1203 mL 0.6014 mL 1.2028 mL 3.0069 mL
40 mM 0.0902 mL 0.4510 mL 0.9021 mL 2.2552 mL
50 mM 0.0722 mL 0.3608 mL 0.7217 mL 1.8041 mL
60 mM 0.0601 mL 0.3007 mL 0.6014 mL 1.5035 mL
80 mM 0.0451 mL 0.2255 mL 0.4510 mL 1.1276 mL
100 mM 0.0361 mL 0.1804 mL 0.3608 mL 0.9021 mL
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2,4-D Butyl ester Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,4-D Butyl ester94-80-4Environmental PollutantsHerbicideEnvironmental Contaminantsprotein synthesisgroundwaterataxiaAcinetobacter sp. ZX02Wistar ratsfishRNAaquatic invertebrates3-indoleacetic acid2,4-dichlorophenoxyacetic acidInhibitorinhibitorinhibit

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