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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
GBA
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "GBA" in MCE Product Catalog:
Cat. No.: HY-101399S
Synonyms: H-γ-Glu-Phe-OH-13C9,15N; γ-Glutamylphenylalanine-13C9,15N
Cat. No.: HY-RS18361
Target:
Research Areas:
Gba2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gba2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24840
Target:
Research Areas:
Gba2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gba2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27250
Target:
Research Areas:
Gba3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gba3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703073
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GBA1; Acid Beta-Glucosidase; Prev. GLUC; Glucocerebrosidase; Prev. GBA; Glucosylceramidase; D-Glucosyl-N-Acylsphingosine Glucohydrolase; Imiglucerase; Lysosomal Cholesterol Glycosyltransferase; Alglucerase; Lysosomal Acid Glucosylceramidase; Beta-GC; Chol
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P88643A
Synonyms: CBG; CBGL1; GLUC; KLRP
Cat. No.: HY-P71650
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GBA3; Cytosolic Beta-Glucosidase-Like Protein 1; Glucosylceramidase Beta 3 (Gene/Pseudogene); Glucosidase, Beta, Acid 3 (Cytosolic); CBGL1; Glucosidase Beta Acid 3; KLrP; Cytosolic GCase; Cytosolic Galactosylceramidase; CBG; Cytosolic Glucosylceramidase;
Species:
Human
Source:
E. coli
Cat. No.: HY-131570
CAS No.: 1997359-63-3
Target:
Research Areas:
JZ-4109 is a β-Glucocerebrosidase (GCase) modulator with an IC50 of 8 nM for wild-type recombinant GCase. JZ-4109 binds to an allosteric site at the GCase dimer interface, stabilizes wild-type and GCase N370S mutant GCase, induces GCase dimerization. JZ-4109 increases GCase protein abundance. JZ-4109 can be used for the research of Parkinson's diseas .
Cat. No.: HY-187642
CAS No.: 303059-39-4
Research Areas:
IGGi-11 is a competitive Gαi inhibitor with a Kd of 5.3 μM for sGαi3. IGGi-11 binds to the GIV interaction region of Gαi3, blocks non-canonical G protein signaling, and does not interfere with Gαi nucleotide processing, Gβγ binding, GPCR activation, or effector regulation. IGGi-11 inhibits the pro-invasive properties of metastatic breast cancer. IGGi-11 can be used in related studies on metastatic breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
