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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
HDM2
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "HDM2" in MCE Product Catalog:
Cat. No.: HY-180331
CAS No.: 1313363-06-2
NVP-CFC218 is a selective TP53-MDM2 inhibitor with a structure and biochemical profile similar to NVP-CGM097 (HY-15954) (IC50 of 1.6 nM: displacing the p53 peptide from the surface of HDM2). It is used to analyze pharmacological sensitivity in cell lines and is also applicable in cancer research [1] [2].
Cat. No.: HY-110088R
CAS No.: 922150-11-6
Target:
Research Areas:
SCH529074 (Standard) is the analytical standard of SCH529074 (HY-110088). This product is intended for research and analytical applications. SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD ( DNA binding domain) with a Ki of 1-2 μM in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma (NSCLC) [2].
Cat. No.: HY-P701593
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MDM2; MDM2 Oncogene, E3 Ubiquitin Protein Ligase; MDM2 Proto-Oncogene; Mdm2 P53 Binding Protein Homolog (Mouse); HDM2; P53-Binding Protein; E3 Ubiquitin-Protein Ligase Mdm2; MDM2 Variant FB55; Oncoprotein Mdm2; MDM2 Variant FB30; MDM2 Proto-Oncogene, E3 U
Species:
Human
Source:
E. coli
Cat. No.: HY-P701594
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDM2; MDM2 Oncogene, E3 Ubiquitin Protein Ligase; MDM2 Proto-Oncogene; Mdm2 P53 Binding Protein Homolog (Mouse); HDM2; P53-Binding Protein; E3 Ubiquitin-Protein Ligase Mdm2; MDM2 Variant FB55; Oncoprotein Mdm2; MDM2 Variant FB30; MDM2 Proto-Oncogene, E3 U
Species:
Human
Source:
E. coli
Cat. No.: HY-P83705
Synonyms: ACTFS antibody;
Double minute 2 protein antibody;
E3 ubiquitin-protein ligase Mdm2 antibody;
HDM 2 antibody;
HDM2 antibody;
HDMX antibody;
MDM 2 antibody;
MDM2 antibody;
MDM2 oncogene E3 ubiquitin protein ligase antibody;
Mdm2 p53 E3 ubiquitin protein ligase homolog antibody;
Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa antibody;
MDM2_HUMAN antibody;
MDM2BP antibody;
Mouse Double Minute 2 antibody;
MTBP antibody;
Murine Double Minute Chromosome 2 antibody;
Oncoprotein Mdm2 antibody;
p53 Binding Protein Mdm2 antibody;
p53-binding protein Mdm2 antibody;
Ubiquitin protein ligase E3 Mdm2 antibody;
Ubiquitin protein ligase E3 Mdm2 antibody
Cat. No.: HY-W174480
CAS No.: 26908-38-3
Target:
Research Areas:
5-deazaflavin is a flavin analogue with redox activity. 5-deazaflavin is a photocatalyst in biological redox systems [2].
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
