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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
88 Results for "
Map4
" in MedChemExpress (MCE) Product Catalog:
Products (88)
88 Results for "Map4" in MCE Product Catalog:
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TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology .
Cat. No.: HY-RS17963
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Map4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM，respectively，in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition .
Cat. No.: HY-RS24434
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Map4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70861
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SIK1 is a MAP4 kinase. The SIK1 MAP4K regulates cell proliferation and cell expansion. SIK1 phosphorylates BIK1 and stabilizes it in a kinase activity-dependent manner. SIK1 Recombinant Human Active Protein Kinase is a recombinant SIK1 protein that can be used to study SIK1-related functions .
Cat. No.: HY-170443
CAS No.: 2736458-30-1
PF-07265028 is a selective hematopoietic progenitor kinase 1 (HPK1/MAP4K1). PF-07265028 can be used in the research of cancer. PF-07265028 shows very potent cellular activity as measured by pSLP76 IC50 (17 nM) .
Cat. No.: HY-E70839
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MAP4K5 (KHS1) belongs to the mammalian Ste20-like serine/threonine kinase family. MAP4K5 plays an important role in regulating a range of cellular responses and is involved in Wnt signaling in hematopoietic cells. KHS1 Recombinant Human Active Protein Kinase is a recombinant KHS1 protein that can be used to study KHS1-related functions .
Cat. No.: HY-145035
CAS No.: 2734168-78-4
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HPK1-IN-9 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-9 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 112) .
Cat. No.: HY-178775
PI4K-IN-3 (Compound 27) is an orally active PI4K inhibitor with an IC50 of 1.9 nM for Plasmodium vivax PI4K. PI4K-IN-3 has no hERG channel inhibition and mammalian cytotoxicity. PI4K-IN-3 has significant selectivity against the human MINK1 and MAP4K4 kinases but with low selectivity against human PI3Kα and PI4Kβ. PI4K-IN-3 has potent antimalarial activity and significantly reduces parasitaemia in NSG mice mouse models of Plasmodium falciparum malaria .
Cat. No.: HY-162922
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MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor (IC50: 80 nM). MAP4K4-IN-6 reduces the c-Jun phosphorylation. MAP4K4-IN-6 has neuroprotective effects. MAP4K4-IN-6 increases the viability of motor neurons. MAP4K4-IN-6 can be used for research of Amyotrophic lateral sclerosis (ALS) .
Cat. No.: HY-RS08071
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MAP4K1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP4K1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08072
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Map4k1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map4k1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08073
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Map4k1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map4k1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08074
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MAP4K2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP4K2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08075
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Map4k2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map4k2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08076
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Map4k2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map4k2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08077
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MAP4K3 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP4K3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08078
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Map4k3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map4k3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08079
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Map4k3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map4k3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
