2763602-67-9
2763602-67-9
Chemical Structure
TGFβRI-IN-3
- CAS No.: 2763602-67-9
- Formula:C28H23N3O2S
- Molecular Weight:465.57
IUPAC Name: 7-(4-(methylsulfonyl)phenyl)-N-(2-(m-tolyl)pyridin-4-yl)quinolin-4-amine
InChIKey: VYDDFPZEAIUBBH-UHFFFAOYSA-N
SMILES: CS(C1=CC=C(C=C1)C2=CC=C3C(NC4=CC=NC(C5=CC(C)=CC=C5)=C4)=CC=NC3=C2)(=O)=O
Biological Activity: TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TGFβRI-IN-3 | 98.21% | TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.63
HY-177946RAF-IN-4 -
Similarity Score 0.57
HY-171986RIPK3-IN-6 -
Similarity Score 0.54
HY-157325RIPK2-IN-5 -
Similarity Score 0.52
HY-W856328N-(4-(Pyridin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide -
Similarity Score 0.52
HY-106515Tebuquine -
Similarity Score 0.52
HY-175015SARS-CoV-2 Mpro-IN-46 -
Similarity Score 0.51
HY-168086LSD1-IN-35 -
Similarity Score 0.51
HY-112451cFMS Receptor Inhibitor II -
Similarity Score 0.51
HY-101872RGSK-872 (Standard) -
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