GSK-872 (Standard)

GSK-872 (Standard) is the analytical standard of GSK-872 (HY-101872). This product is intended for research and analytical applications. GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury.

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  • CAS No.: 1346546-69-7
  • 화학식: C19H17N3O2S2
  • 분자량:383.49
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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