2478592-86-6
Chemical Structure
TNIK&MAP4K4-IN-1
- CAS No.: 2478592-86-6
- Formula:C25H23FN4O3
- Molecular Weight:446.47
InChIKey: KDQBVTAHXVNGBG-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=C(C3=CC=C(F)C=C3)N=CN2C4CCCC4)O1)NC5=C(OC)C=NC=C5
Biological Activity: TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM,respectively,in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition[1].
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TNIK&MAP4K4-IN-1 | 99.73% | TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM,respectively,in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition. | ||||||||||||||||||||
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Keywords