500 Results for "

CD3

" in MedChemExpress (MCE) Product Catalog:
Products (500)

500 Results for "CD3" in MCE Product Catalog:

Emedastine-13C,d3 fumarate
Emedastine-13C,d3 fumarate
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Cat. No.: HY-108411S
CAS No.: 2934886-28-7
Emedastine- 13C,d3 fumarate is the 13C- and deuterium labeled Emedastine. Emedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis [3].
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Tegaserod-13C,d3 maleate
Tegaserod-13C,d3 maleate
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Cat. No.: HY-14153AS
Synonyms: SDZ-HTF-919-13C,d3; HTF-919-13C,d3
Tegaserod- 13C,d3 (maleate) is the 13C- and deuterium labeled Tegaserod (maleate). Tegaserod maleate is a selective 5-HT4 receptor partial agonist and a 5-HT2B receptor antagonist. Tegaserod maleate exhibits a promotile effect throughout the gastrointestinal (GI) tract .
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Osimertinib-13C,d3
Osimertinib-13C,d3
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Cat. No.: HY-15772S1
CAS No.: 2254100-49-5
Synonyms: AZD-9291-13C,d3; Mereletinib-13C,d3
Osimertinib- 13C,d3 is the deuterium and 13C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.
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Methyl Eugenol-13C,d3
Methyl Eugenol-13C,d3
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Cat. No.: HY-N6996S
Methyl Eugenol- 13C,d3 is the 13C- and deuterium labeled Methyl Eugenol. Methyl Eugenol, a phenylpropanoid chemical in leaves, fruits, stems, and/or roots, may be released when that corresponding part of a plant is damaged as a result of feeding by an herbivore. Methyl Eugenol is used for male annihilation of the oriental fruit fly .
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Pacanalotamab
Pacanalotamab
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Cat. No.: HY-P99798
CAS No.: 2251756-52-0
Synonyms: AMG 420; BI-836909

Target:  

CD3

Research Areas:  

Cancer

Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .
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Pazopanib-13C,d3 hydrochloride
Pazopanib-13C,d3 hydrochloride
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Cat. No.: HY-12009S
CAS No.: 1261398-44-0
Purity:  97.51%
Synonyms: GW786034-13C,d3 hydrochloride
Pazopanib- 13C,d3 (hydrochloride) is the deuterium and 13C labeled Pazopanib hydrochloride . Pazopanib Hydrochloride (GW786034 Hydrochloride) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with an IC50 of 10, 30, 47, 84, 74, 140 and 146 nM, respectively [3].
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Trelagliptin-13C,d3
Trelagliptin-13C,d3
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Cat. No.: HY-15408S
CAS No.: 2707203-34-5
Synonyms: SYR-472-13C,d3
Trelagliptin-13C,d3 is a deuterated labeled Trelagliptin . Trelagliptin (SYR-472) is a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM. Trelagliptin succinate improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM) .
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Epinastine-13C,d3 hydrobromide
Epinastine-13C,d3 hydrobromide
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Cat. No.: HY-B0640S
Synonyms: WAL801-13C,d3 hydrobromide
Epinastine- 13C,d3 (hydrobromide) is the 13C- and deuterium labeled Epinastine. Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action [3] .
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Nicergoline-13C,d3
Nicergoline-13C,d3
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Cat. No.: HY-B0702S
Nicergoline- 13C,d3 is the 13C- and deuterium labeled Nicergoline. Nicergoline, an ergoline derivative ester of bromonicotinic acid, is a potent, selective and orally active antagonist of α1A-adrenoceptor. Nicergoline has vasodilator effects. Nicergoline also has ameliorative effects on cognitive function in mouse models of Alzheimer's disease .
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Pazopanib-13C,d3
Pazopanib-13C,d3
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Cat. No.: HY-10208S1
CAS No.: 1261734-88-6
Synonyms: GW786034-13C,d3
Pazopanib- 13C,d3 is the deuterium and 13C labeled Pazopanib . Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively [3].
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Etoricoxib-13C,d3
Etoricoxib-13C,d3
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Cat. No.: HY-15321S1
CAS No.: 2748267-73-2
Synonyms: MK-0663-13C,d3; L-791456-13C,d3
Etoricoxib- 13C,d3 is the 13C- and deuterium labeled Etoricoxib. Etoricoxib (MK-0663) is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.
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Medetomidine-13C,d3 hydrochloride
Medetomidine-13C,d3 hydrochloride
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Cat. No.: HY-17034BS1
CAS No.: 1216630-06-6
Synonyms: MPV785-13C,d3
Medetomidine-13C,d3 (hydrochloride) is a deuterated labeled Medetomidine (hydrochloride) . Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels [3] .
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Erythromycin-13C,d3
Erythromycin-13C,d3
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Cat. No.: HY-B0220S1
CAS No.: 2378755-50-9
Erythromycin- 13C,d3 is the 13C- and deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .
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Methocarbamol-13C,d3
Methocarbamol-13C,d3
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Cat. No.: HY-B0262S2
CAS No.: 2747917-88-8
Methocarbamol- 13C,d3 is the 13C- and deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research [3].
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Lamotrigine-13C,d3
Lamotrigine-13C,d3
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Cat. No.: HY-B0495S1
CAS No.: 2517756-06-6
Synonyms: LTG-13C,d3; BW430C-13C,d3
Lamotrigine- 13C,d3 is the 13C- and deuterium labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy,?focal seizure, et al .
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Carprofen-13C,d3
Carprofen-13C,d3
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Cat. No.: HY-B1227S1
CAS No.: 2012598-34-2
Carprofen- 13C,d3 is the deuterium and 13C labeled Carprofen . Carprofen is a nonsteroid anti-inflammatory agent, acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 μM, 22.3 μM and 78.6 μM for COX-2, COX-1 and FAAH, respectively [3] .
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Regorafenib-13C,d3
Regorafenib-13C,d3
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Cat. No.: HY-10331S1
Synonyms: BAY 73-4506-13C,d3
Regorafenib- 13C,d3 is the 13C- and deuterium labeled Regorafenib. Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively.
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Oxytetracycline-13C,d3 hydrochloride
Oxytetracycline-13C,d3 hydrochloride
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Cat. No.: HY-W755036
Oxytetracycline-13C,d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride (HY-B0275A). Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity [3] .
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Flurbiprofen-13C,d3
Flurbiprofen-13C,d3
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Cat. No.: HY-10582S2
CAS No.: 2747917-55-9
Synonyms: dl-Flurbiprofen-13C,d3
Flurbiprofen- 13C,d3 is the 13C- and deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer [3].
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Asenapine-13C,d3
Asenapine-13C,d3
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Cat. No.: HY-10121S2
CAS No.: 2747915-30-4
Synonyms: Org 5222-13C,d3
Asenapine- 13C,d3 is 13C and deuterated labeled Asenapine (HY-10121). Asenapine (Org 5222), an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine can be used in the research of schizophrenia and bipolar disorder .
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