68 Results for "

C terminus

" in MedChemExpress (MCE) Product Catalog:
Products (68)

68 Results for "C terminus" in MCE Product Catalog:

Cat. No.: HY-E70566
Target:  

Ser/Thr Protease

Research Areas:  

Others

Protease (Fab Cleaving) is a serine protease expressed recombinantly in E.coli with a 6×His tag at the C-terminus. Protease (Fab Cleaving) specifically digests human IgG1 at a single site above the hinge, generating intact Fab and Fc fragments within two hours without reducing conditions.
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Cat. No.: HY-P5007
CAS No.: 78362-34-2
Research Areas:  

Cardiovascular Disease

Copeptin (human) is a peptide biochemical reagent corresponding to the 39 amino acid sequence at the C-terminus of human pre-provasopressin, which serves as a stable surrogate biomarker reflecting the secretion of arginine vasopressin (AVP). Copeptin (human) can be used in studies related to AVP secretion, fluid and osmotic homeostasis, stress responses, and cardiovascular biomarkers .
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Cat. No.: HY-P11314
CAS No.: 241145-90-4
Target:  

Amyloid-β

ABri, 34 amino acids long, is an Amyloid subunit with certain degree of N- and C-terminal heterogeneity and no sequence identity to any known amyloid protein. ABri is devoid of glycine, methionine, proline, aspartic acid, tryptophane, tyrosine and glutamine, featuring pyroglutamate at its N-terminus. ABri can be used for cerebral hemorrhages, ischemic infarction and Alzheimer disease research .
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Cat. No.: HY-W440807
CAS No.: 2353409-68-2
Target:  

Liposome

Research Areas:  

Others

Oleoyl-Gly-Lys-(m-PEG11)-NH2 is a PEG-lipid molecule featuring an oleoyl amide linked to a Gly-Lys dipeptide and a methoxy PEG11 chain on the C-terminus of the lysine. The lysine primary amine may be used in a wide variety of reactions with carboxylic acids, NHS esters, and carbonyl groups. The PEG linker provides aqueous solubility.
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Cat. No.: HY-P5439
Target:  

PKC MARCKS

Research Areas:  

Others

Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
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Cat. No.: HY-P1195A
Target:  

iGluR

Research Areas:  

Neurological Disease

PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
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Cat. No.: HY-P991073

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

MEDI-1814 is a fully human IgG1 antibody that targets the C terminus of Aβ42. MEDI-1814 binds to and sweeps away the circulated Aβ peptides, hence, restricting them from aggregating into toxic oligomers. MEDI-1814 can be used for the study of Alzheimer's diseases. The isotype control for MEDI-1814 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Research Areas:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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Cat. No.: HY-P1055
CAS No.: 1315378-76-7
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep2-SVKE is an inactive control peptide for pep2-SVKI (HY-P1056). Pep2-SVKE is an inhibitory peptide corresponding to the last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Pep2-SVKE does not block AMPA-mediated [ 3H]DA exocytosis. Pep2-SVKE does not bind to GRIP or PICK43 and does not block retention of PICK1 by GST-GluR2 and LTD [1] [2] [3] [4] [5].
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Cat. No.: HY-12135
CAS No.: 1239513-63-3
Research Areas:  

Cancer

Poloxipan is a pan-specific polo-like kinase (PLK) inhibitor that can inhibit a non-catalytic region at the C-terminus called the Polo-box domain (PBD) found in kinases. The IC50 values for Poloxipan against the PBDs of PLK-1/2/3 are 3.2 μM, 1.7 μM, and 3.0 μM, respectively. Poloxipan also inhibits other phospho-tyrosine binding domains, such as the forkhead-associated (FHA) domain of CHK-2, the WW domain of peptidyl-prolyl cis/trans isomerase (PIN1), and the phospho-tyrosine binding domains of STAT1/3/5 and lymphocyte-specific protein tyrosine kinase's SH2 domain. Poloxipan can be used in cancer research .
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Cat. No.: HY-P4074
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Anti-BetaGamma, a peptide, is MPS-Phosducin-like protein C terminus .
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Cat. No.: HY-P2553
CAS No.: 917103-17-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Histone H3 (116-136), C116-136 is a peptide spaning the C-terminus of histone H3, amino acids 116 to 136 .
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Cat. No.: HY-P10739E
Research Areas:  

Others

YRLGRWC is a scrambled control of WYRGRLC (HY-P10739C), and it is synthesized by conjugating cysteine to the carboxyl (C-terminus) of YRLGRW (HY-P10739D) .
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Cat. No.: HY-P12135
CAS No.: 3061967-85-6
Target:  

Bacterial

Research Areas:  

Infection

Epaganan is a modified antimicrobial peptide, a derivative of the natural peptide Tachyplesin-1 with an aspartic acid residue added to its C-terminus. Epaganan can be used in veterinary research .
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Cat. No.: HY-117192
CAS No.: 1052515-37-3
Target:  

HSP Fungal

Research Areas:  

Infection

NSC145366 monohydrochloride is a Hsp90 C-terminal inhibitor. NSC145366 monohydrochloride directly interacts with the C-terminus of Hsp90 and inhibits its chaperone activity. NSC145366 monohydrochloride strongly inhibits the growth of Saccharomyces cerevisiae cog7Δ and cog8Δ strains .
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Cat. No.: HY-185909
Target:  

Phosphoramidites

Research Areas:  

Others

Dodecanamido C7 Phosphoramidite is a lipophilic modifying reagent used for solid-phase oligonucleotide synthesis. Dodecanamido C7 Phosphoramidite can introduce a lauric acid (dodecanoic acid) side chain at the terminus or interior of DNA or RNA chains, and is mainly used to enhance the cell membrane penetration ability and delivery efficiency of nucleic acid reagents.
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Cat. No.: HY-176277S
Synonyms: FPB,human-(Val-13C5,15N, Arg-13C6,15N4) TFA
Research Areas:  

Inflammation/Immunology

Fibrinopeptide B, human-(Val- 13C5, 15N, Arg- 13C6, 154) TFA is the 13C- and 15N-labeled Fibrinopeptide B, human (HY-P1493). Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin .
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Cat. No.: HY-P11284B
CAS No.: 1418155-47-1
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

TGN, Cys modified is a cysteine modified TGN (HY-P11284) on the C-terminus. TGN, a 12-amino acid ligand, is a BBB-penetrating peptide. TGN can be used as a drug delivery vehicle for Alzheimer's disease research .
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Cat. No.: HY-E70981
Research Areas:  

Metabolic Disease

Alanine Racemase, Bacillus stearothermophilus (EC 5.1.1.1) is involved in alanine, aspartate and D-alanine metabolism. Alanine Racemase, Bacillus stearothermophilus (EC 5.1.1.1) monomer is composed of two domains, an eight-stranded α/β barrel at the N-terminus and a C-terminal domain.
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Cat. No.: HY-P11921
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

FEAEHNLALQTL-GGGSC is a scrambled control peptide targeting the Glypican-3 (GPC3) polypeptide, with a GGGSC linker at its C-terminus. FEAEHNLALQTL-GGGSC serves as a negative control in both hepatoma cells and tumor-bearing mouse models, lacks specific targeting ability, and can be used for hepatocellular carcinoma-related research .
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