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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
148 Results for "
thiol-groups
" in MedChemExpress (MCE) Product Catalog:
Products (148)
148 Results for "thiol-groups" in MCE Product Catalog:
Cat. No.: HY-162159
CAS No.: 10061-65-1
Target:
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Ac-Cys-NHMe is a Cys dipeptide with thiol group .
Cat. No.: HY-D1526
CAS No.: 50539-45-2
Cat. No.: HY-129994
CAS No.: 82494-50-6
Synonyms: S-Nitroso-coenzyme A; SNO-CoA; SNO-coenzyme A
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S-Nitroso-CoA (S-Nitroso-coenzyme A) is a nitrosothio compound that is coenzyme A in which the thiol group is replaced by a nitrososulfanediyl group .
Cat. No.: HY-140652
Target:
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Amine-PEG3400-thiol is a conjugate containing amino, PEG and thiol groups, used for drug delivery, material modification and chemical synthesis.
Cat. No.: HY-17525
CAS No.: 163269-30-5
Research Areas:
Bethoxazin is a yeast DNA topoisomerase II inhibitor with an IC50 of 5.3 μM, and also a broad-spectrum industrial microbicide and covalent adduct-forming agent. Bethoxazin inhibits the catalytic activity of yeast DNA topoisomerase II by reacting with the key free cysteine thiol group on the enzyme. Bethoxazin forms covalent adducts with molecules containing free thiol groups. Bethoxazin inhibits the growth of yeast cells. Bethoxazin can be used in studies related to the growth of fungi, molds and algae .
Cat. No.: HY-W395122
CAS No.: 1345681-74-4
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Mal-PEG1-PNP-carbonate is a amine-reactive compound. PNP is a good leaving group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Cat. No.: HY-W800682
CAS No.: 2639395-49-4
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Bis-Sulfone-PEG4-acid is a reagent with a sulfone and an acid. The sulfone group can be conjugated with thiol groups of proteins. The terminal acid reacts with primary amines with the help of activators (EDC or HATU) to from stable amide bonds.
Cat. No.: HY-CE00399
CAS No.: 917-43-1
Synonyms: (S)-3-Hydroxylauroyl-coenzyme A
Target:
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(S)-3-Hydroxylauroyl-CoA ((S)-3-Hydroxylauroyl-coenzyme A) is a hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (S)-3-hydroxydodecanoic acid.
Cat. No.: HY-CE00476
CAS No.: 117249-46-4
Synonyms: (3R)-Hydroxyvaleryl-coenzyme A
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(R)-3-Hydroxyvaleryl-CoA ((3R)-Hydroxyvaleryl-coenzyme A) is a 3-hydroxy fatty acyl-CoA resulting from the formal condensation of the thiol group of coenzyme A with the carboxy group of (R)-3-hydroxypentanoic acid.
Cat. No.: HY-W591975
CAS No.: 2785323-77-3
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Alkyne maleimide is a bifunctional linker reagent with a terminal malimide group and a propargyl group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
Cat. No.: HY-CE00299
CAS No.: 226558-54-9
Synonyms: (3S)-3-Hydroxyicosanoyl-coenzyme A
Target:
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(3S)-3-Hydroxyicosanoyl-CoA ((3S)-3-Hydroxyicosanoyl-coenzyme A) is a 3-hydroxyicosanoyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (3S)-hydroxyicosanoic acid.
Cat. No.: HY-W800817
CAS No.: 2748945-56-2
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TCO-PEG4-maleimide is a click chemistry building block containing a TCO moiety and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond. TCO moiety is very reactive with tetrazine (3rd generation click chemistry).
Cat. No.: HY-168938
Cat. No.: HY-136386R
CAS No.: 26117-28-2
Category:
Cat. No.: HY-W800828
CAS No.: 2512227-27-7
Target:
Research Areas:
Iodoacetamido-PEG3-NHS ester is a PEG reagent containing an Iodoacetamide group and a Boc-protected amino group. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Cat. No.: HY-CE00465
CAS No.: 875613-67-5
Synonyms: 1,4-Dihydroxy-2-naphthoyl-coenzyme A
Target:
Research Areas:
1,4-Dihydroxy-2-naphthoyl-CoA (1,4-Dihydroxy-2-naphthoyl-coenzyme A) is an acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 1,4-dihydroxy-2-naphthoic acid.
Cat. No.: HY-D2150
Cat. No.: HY-CE00413
Synonyms: (3S)-3-Hydroxyoleoyl-coenzyme A
Target:
Research Areas:
(3S)-3-Hydroxyoleoyl-CoA ((3S)-3-Hydroxyoleoyl-coenzyme A) is a 3-hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (3S)-3-hydroxyoleic acid.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
