![[Nle8,18,Tyr34]-pTH (3-34) amide (bovine)](https://file.medchemexpress.com/product_pic/hy-p10313.gif "Click to View [Nle8,18,Tyr34]-pTH (3-34) amide (bovine) Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
101 Results for "
parathyroid-hormone
" in MedChemExpress (MCE) Product Catalog:
Products (101)
101 Results for "parathyroid-hormone" in MCE Product Catalog:
Cat. No.: HY-P71244
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTH1R; PTH/PTHr Receptor; Prev. PTHR1; parathyroid hormone/parathyroid hormone-Related Protein Receptor; Prev. PTHR; Seven Transmembrane Helix Receptor; parathyroid hormone/parathyroid hormone-Related Peptide Receptor; EKNS; PTH/PTHrP Type I Receptor; PFE
Species:
Human
Source:
HEK293
Cat. No.: HY-P705968
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTH1R; PTH/PTHr Receptor; Prev. PTHR1; parathyroid hormone/parathyroid hormone-Related Protein Receptor; Prev. PTHR; Seven Transmembrane Helix Receptor; parathyroid hormone/parathyroid hormone-Related Peptide Receptor; EKNS; PTH/PTHrP Type I Receptor; PFE
Species:
Rat
Source:
HEK293
Cat. No.: HY-P4857A
Target:
Research Areas:
pTH-Related Protein (7-34) amide (human, mouse, rat) acetate is a potent antagonist of parathyroid hormone (PTH) .
Cat. No.: HY-179356
CAS No.: 1413439-62-9
Target:
Research Areas:
Octadecyl β-D-glucopyranosiduronic acid (Compound 9) is a parathyroid hormone 1 receptor (PTH1R) activator, with a pEC50 value > 9. Octadecyl β-D-glucopyranosiduronic acid can be used for research on hypoparathyroidism .
Cat. No.: HY-100856R
CAS No.: 1613373-33-3
Target:
Research Areas:
PCO371 (Standard) is the analytical standard of PCO371 (HY-100856). This product is intended for research and analytical applications. PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
Cat. No.: HY-P10313
CAS No.: 64297-16-1
Synonyms: [Nle8'18,Tyr34]bPTH (3-34) amide
Target:
Research Areas:
Cat. No.: HY-118668
CAS No.: 1117772-52-7
ABD-350 is an antiresorptive agent that inhibits osteoclast activity without affecting osteoblast activity and preventing ovariectomy-induced bone loss. ABD-350 inhibits NF-κB ligand-induced inhibitor of NF-κB phosphorylation, leading to osteoclast apoptosis, but has no inhibitory effect on osteoblast function, effectively preventing bone loss in ovariectomized mice, and does not inhibit parathyroid hormone-induced bone formation.
Cat. No.: HY-14401B
CAS No.: 787584-62-7
Synonyms: CLTX-305 sodium; JTT-305 sodium; MK-5442 sodium
Target:
Research Areas:
Encaleret (CLTX-305) sodium is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 12 nM. Encaleret sodium exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret sodium can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1 .
Cat. No.: HY-113875
CAS No.: 101470-42-2
Synonyms: Collagenase inhibitor CI-2
Z-Acp-leu-metyr-MA (Collagenase inhibitor CI-2) is a mammalian tissue collagenase inhibitor, with an IC50 of 200 μM against human rheumatoid synovial collagenase, 30 μM against mouse bone collagenase, 60 μM against rabbit bone proteoglycanase, 25 μM against mouse bone neutral protease, and >100 μM against rabbit macrophage neutral protease. Z-Acp-leu-metyr-MA inhibits parathyroid hormone-induced bone collagen matrix resorption in cultured embryonic mouse calvariae .
Cat. No.: HY-109106AR
CAS No.: 2052969-18-1
Synonyms: SK-1403 (Standard); AJT240 (Standard); PLS240 (Standard)
Target:
Research Areas:
Upacicalcet sodium (Standard) is the analytical standard of Upacicalcet (sodium) (HY-109106A). This product is intended for research and analytical applications. Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic Kidney disease (CKd). Upacicalcet sodium is useful for studying SHPT .
Cat. No.: HY-16497
CAS No.: 848084-84-4
Synonyms: PCK 3145 TFA
Research Areas:
Tigapotide TFA (PCK-3145 TFA) is a synthetic 15-mer peptide derived from prostate-secretory protein, and acts as an antineoplastic agent. Tigapotide TFA inhibits tumor growth, experimental bone metastasis, and malignancy-associated hypocalcemia. Tigapotide TFA induces Apoptosis in prostate cancer cells and tumors, and suppresses the growth of prostate cancer cells. Tigapotide TFA inhibits the production of parathyroid hormone-related protein (PTHrP) in tumors and plasma. Tigapotide TFA reduces plasma calcium levels in hypercalcemic tumor-bearing rats. Tigapotide TFA is applicable for the research of prostate cancer and malignancy-associated hypercalcemia .
Cat. No.: HY-10002AR
CAS No.: 61476-45-7
Synonyms: 1α,25-Dihydroxy-3-epi-vitamin-D3 (Standard)
Target:
Research Areas:
(1S)-Calcitriol (Standard) is the analytical standard of (1S)-Calcitriol (HY-10002A). This product is intended for research and analytical applications. (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
Cat. No.: HY-159978
CAS No.: 1628848-73-6
Synonyms: EOS789
Target:
Research Areas:
Atidafonat is an orally active sodium-dependent phosphate transporter inhibitor, with IC50 values of 6.8, 1.5, and 1.7 μM against human NaPi-IIb, PiT-1, PiT-2, respectively; and IC50 values of 3.9, 1.9, and 1.7 μM against rat NaPi-IIb, PiT-1, PiT-2, respectively. Atidafonat inhibits intestinal phosphate absorption, increases fecal phosphate excretion, reduces urinary phosphate excretion, and decreases the levels of serum phosphate, FGF23, and adult parathyroid hormone. Atidafonat ameliorates ectopic thoracic aortic calcification, renal injury and hyperphosphatemia, and inhibits the expression of fibrosis markers. Atidafonat can be used for the research of hyperphosphatemia and chronic kidney disease-mineral and bone disorder (CKD-MBD) .
Cat. No.: HY-10002AS
CAS No.: 1539301-06-8
Synonyms: 1α,25-Dihydroxy-3-epi-vitamin D3-d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
