101 Results for "

parathyroid-hormone

" in MedChemExpress (MCE) Product Catalog:
Products (101)

101 Results for "parathyroid-hormone" in MCE Product Catalog:

Cat. No.: HY-10003AR
CAS No.: 58028-00-5
1α-Hydroxy-3-epi-vitamin D3 (Standard) is the analytical standard of 1α-Hydroxy-3-epi-vitamin D3 (HY-10003A). This product is intended for research and analytical applications. 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .
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Cat. No.: HY-P4856
CAS No.: 120298-73-9
Target:  

PTHR PKC

Research Areas:  

Endocrinology

pTH-Related Protein (1-40) (human, mouse, rat) stimulates calcium uptake in rat intestinal cells through PTHR1 receptor and PKCα/β signaling pathways. pTH-Related Protein (1-40) up-regulates parathyroid hormone 1 receptor (PTHR1) protein, four transcellular calcium transporters, potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1) and plasma membrane calcium ATPase 1 (PMCA1) .
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Cat. No.: HY-P4827
CAS No.: 521986-14-1
Target:  

PTHR

Research Areas:  

Metabolic Disease

pTH (1-84) dog is a biologically active full-length canine parathyroid hormone, as well as an agonist of PTHR. pTH (1-84) dog can be detected by the "intact" PTH (W-PTH) assay, thus effectively distinguishing inactive C-terminal fragments. In terms of metabolic regulation, it rapidly and persistently stimulates hepatic glucose release, hepatic alanine uptake, and alanine-based gluconeogenesis in conscious fasted dogs, and causes a secondary increase in circulating canine insulin levels due to enhanced glucose release. However, high doses of pTH (1-84) (dog) may induce adverse reactions such as hypercalcemia in dogs. Based on the above characteristics, this hormone can be widely used in studies related to canine hyperadrenocorticism (HAC) .
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Cat. No.: HY-P1252A
Research Areas:  

Metabolic Disease

Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
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Cat. No.: HY-176944
CAS No.: 3106850-44-3
Target:  

PTHR

Research Areas:  

Metabolic Disease Endocrinology

PTH1R agonist 2 (example 3) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 2 can be used for research of hypoparathyroidism and osteoporosis .
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Cat. No.: HY-14752
CAS No.: 753449-67-1
Synonyms: SB 751689
Target:  

CaSR

Research Areas:  

Metabolic Disease Endocrinology

Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .
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Cat. No.: HY-15104
CAS No.: 702686-96-2
Synonyms: SB 751689A
Target:  

CaSR

Research Areas:  

Metabolic Disease Endocrinology

Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .
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Cat. No.: HY-10003A
CAS No.: 58028-00-5
Purity:  99.30%
Research Areas:  

Metabolic Disease

1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .
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Cat. No.: HY-176945
CAS No.: 3106619-38-6
Target:  

PTHR

Research Areas:  

Metabolic Disease

PTH1R agonist 3 (Example 47) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value of less than 6. PTH1R agonist 3 can be used for the study of bone diseases, such as osteoporosis .
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Cat. No.: HY-32351B
CAS No.: 73809-05-9
Synonyms: 3-epi-25-Hydroxy cholecalciferol
Target:  

PTHR

Research Areas:  

Endocrinology

3-epi-25-hydroxy Vitamin D3 is the C-3 epimer of 25-hydroxy vitamin D3.1 Dietary administration of 3-epi-25-hydroxy vitamin D3 (0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats.
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Cat. No.: HY-125064
CAS No.: 268741-43-1
Target:  

Src

Research Areas:  

Cancer

AP22408 is a nonpeptide inhibitor against Src SH2 with an IC50 value of 0.3 μM. AP22408 inhibits rabbit osteoclast-mediated resorption of dentine, exhibits bone-targeting properties based on a hydroxyapatite adsorption assay and demonstrates in vivo antiresorptive activity in a parathyroid hormone-induced rat model. AP22408 is proming for rasearch of osteoporosis and other bone-related diseases such as Paget’s disease, osteolytic bone metastasis and hypercalcemia associated with malignancy .
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Cat. No.: HY-109106
CAS No.: 1333218-50-0
Synonyms: SK-1403 free acid; AJT240 free acid; PLS240 free acid
Target:  

CaSR

Research Areas:  

Endocrinology

Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .
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Cat. No.: HY-P4690
CAS No.: 81306-64-1
Research Areas:  

Endocrinology

pTH (13-34) (human) is apTH ((Human parathyroid hormone) fragment.
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Cat. No.: HY-P4692
CAS No.: 85568-24-7
Research Areas:  

Endocrinology

pTH (1-44) (human) is apTH ((Human parathyroid hormone) fragment.
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Cat. No.: HY-P4696
CAS No.: 51257-86-4
Research Areas:  

Endocrinology

pTH (3-34) (bovine) is apTH ((Human parathyroid hormone) fragment.
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Cat. No.: HY-P4697
CAS No.: 64421-69-8
Research Areas:  

Endocrinology

pTH (44-68) (human) is apTH ((Human parathyroid hormone) fragment.
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Cat. No.: HY-P4700
CAS No.: 89439-30-5
Research Areas:  

Endocrinology

pTH (53-84) (human) is apTH ((Human parathyroid hormone) fragment.
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Cat. No.: HY-P4762
CAS No.: 86292-93-5
Target:  

Inhibitory Antibodies

Research Areas:  

Others

(TYR34)-PTH (7-34) AMIDE (BOVINE) is a peptide derivative of Parathyroid Hormone (PTH) .
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Cat. No.: HY-P4715
CAS No.: 213779-11-4
Target:  

PTHR

Research Areas:  

Endocrinology

(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) is a peptide and can be used as a parathyroid hormone (PTH) receptor ligand .
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Cat. No.: HY-P4800
CAS No.: 137348-10-8
Synonyms: Human PTHrP(107-139)
Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .
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