753449-67-1
753449-67-1
Chemical Structure
Ronacaleret
Synonym(s): SB 751689
- CAS No.: 753449-67-1
- Formula:C25H31F2NO4
- Molecular Weight:447.51
IUPAC Name: (R)-3-(3-(3-((1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)-4,5-difluorophenyl)propanoic acid
InChIKey: FQJISUPNMFRIFZ-HXUWFJFHSA-N
SMILES: O=C(O)CCC1=CC(F)=C(F)C(OC[C@H](O)CNC(C)(C)CC2CC3=C(C=CC=C3)C2)=C1
Biological Activity: Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis[1].
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Ronacaleret | Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis. | |||||||||||||||||||||
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