164 Results for "

Folate Receptor

" in MedChemExpress (MCE) Product Catalog:
Products (164)

164 Results for "Folate Receptor" in MCE Product Catalog:

Cat. No.: HY-174960D
Synonyms: 6-Arm-PEG3400-Folate
6-Arm-PEG3400-FA (6-Arm-PEG3400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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Cat. No.: HY-174960E
Synonyms: 6-Arm-PEG5000-Folate
6-Arm-PEG5000-FA (6-Arm-PEG5000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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Cat. No.: HY-174960H
Synonyms: 6-Arm-PEG10000-Folate
6-Arm-PEG10000-FA (6-Arm-PEG10000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
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Cat. No.: HY-P992515

Research Areas:  

Cancer

ZW-191 Antibody is a humanized IgG1 antibody targeting folate receptor α (FRα). ZW-191 Antibody is conjugated with MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360) to generate the antibody-drug conjugate (ADC) ZW-191 (HY-185743). ZW-191 Antibody-based ADC exerts a potent bystander effect on both antigen-positive and antigen-negative cells. ZW-191 Antibody is applicable to research related to ovarian cancer, non-small cell lung cancer, endometrial cancer, and triple-negative breast cancer .
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Cat. No.: HY-128939
CAS No.: 1059477-92-7
Target:  

Antifolate

Research Areas:  

Cancer

EC0488 is used to synthesize EC0531 with folate receptor (FR)-specific and anti-tumor activities .
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Cat. No.: HY-129880
CAS No.: 55383-37-4
Synonyms: Deacetylvinblastine hydrazide; DAVLBH
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Desacetylvinblastine hydrazide (Deacetylvinblastine hydrazide; DAVLBH) is an active component of EC145, a folate-targeted drug conjugate. Desacetylvinblastine hydrazide interferes with the formation of the mitotic spindle, and thus inhibits cell division and leads to cell death. Desacetylvinblastine hydrazide exhibits antitumor activity against folate receptor (FR)-positive tumor .
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Cat. No.: HY-W888710A
Synonyms: Folate-PEG400-COOH
FA-PEG400-COOH (Folate-PEG400-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-W888710B
Synonyms: Folate-PEG600-COOH
FA-PEG600-COOH (Folate-PEG600-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-W888710C
Synonyms: Folate-PEG1000-COOH
FA-PEG1000-COOH (Folate-PEG1000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-W888710D
Synonyms: Folate-PEG2000-COOH
FA-PEG2000-COOH (Folate-PEG2000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-W888710E
Synonyms: Folate-PEG3400-COOH
FA-PEG3400-COOH (Folate-PEG3400-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-W888710H
Synonyms: Folate-PEG5000-COOH
FA-PEG5000-COOH (Folate-PEG5000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-W888710I
Synonyms: Folate-PEG10000-COOH
FA-PEG10000-COOH (Folate-PEG10000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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Cat. No.: HY-13616
CAS No.: 479578-27-3
Synonyms: EC 20
Research Areas:  

Cancer

Etarfolatide (EC 20) is a valuable noninvasive imaging agent. Etarfolatide identifies folate receptor expression. Etarfolatide can be used in research on ovarian cancer and disease diagnosis after being radiolabeled .
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Cat. No.: HY-10822
CAS No.: 501332-69-0
Synonyms: BGC 945; ONX-0801; CB 300945
Target:  

Thymidylate Synthase

Research Areas:  

Cancer

Idetrexed (ONX 0801) is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
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Cat. No.: HY-185774
Research Areas:  

Cancer

ADC Control Human IgG1 (D356E/L358M)-LNK4 (DAR8) is a control ADC with a drug-to-antibody ratio (DAR) of 8, consisting of Human IgG1 (D356E/L358M) kappa, Isotype Control (HY-P990100), which does not specifically bind to FRα, and LNK4-S (HY-170400). ADC Control Human IgG1 (D356E/L358M)-LNK4 (DAR8) serves as the isotype control for Farletuzumab-LNK4-S (DAR8) (HY-185773) .
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Cat. No.: HY-185774A
Research Areas:  

Cancer

ADC Control Human IgG1 (D356E/L358M)-LNK4 (DAR4) is a control antibody-drug conjugate (ADC) with a drug-to-antibody ratio (DAR) of 4, formed by the conjugation of Human IgG1 (D356E/L358M) kappa, Isotype Control (HY-P990100) and LNK4-S (HY-170400). ADC Control Human IgG1 (D356E/L358M)-LNK4 (DAR4) serves as the isotype control for Farletuzumab-LNK4-S (DAR4) (HY-185773A) .
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Cat. No.: HY-179189
Synonyms: Folate-PEG400-ACA
FA-PEG400-ACA (Folate-PEG400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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Cat. No.: HY-179189A
Synonyms: Folate-PEG600-ACA
FA-PEG600-ACA (Folate-PEG600-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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Cat. No.: HY-179189B
Synonyms: Folate-PEG1000-ACA
FA-PEG1000-ACA (Folate-PEG1000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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