2 Results for "

γ-Glu-Tyr

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "γ-Glu-Tyr" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P4633
CAS No.: 7432-23-7
γ-Glu-Tyr is an orally active gut microbiota-derived metabolite and a competitive DPP-IV inhibitor with an IC50 of 6.77 mM against hDPP-IV. γ-Glu-Tyr weakly activates hCaSR. γ-Glu-Tyr decreases colonic pro-inflammatory cytokine (IL-6, IL-1β, TNF-α) levels. γ-Glu-Tyr activates the cAMP/PKA signaling pathway and inhibits NF-κB phosphorylation, thereby reducing inflammatory responses. γ-Glu-Tyr can be used for research on type 2 diabetes and ulcerative colitis .
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Cat. No.: HY-P4633A
CAS No.: 2417507-97-0
Research Areas:  

Metabolic Disease

D-γ-Glu-Tyr is a D-isomer of γ-Glu-Tyr (HY-P4633), the difference being the γ-Glu content.γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet .
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