2. Others Metabolic Enzyme/Protease
  3. Drug Isomer Dipeptidyl Peptidase
  4. D-γ-Glu-Tyr

D-γ-Glu-Tyr is a D-isomer of γ-Glu-Tyr (HY-P4633), the difference being the γ-Glu content.γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet.

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Custom Peptide Synthesis

D-γ-Glu-Tyr

D-γ-Glu-Tyr Chemical Structure

CAS No. : 2417507-97-0

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Based on 1 publication(s) in Google Scholar

Other Forms of D-γ-Glu-Tyr:

D-γ-Glu-Tyr Related Antibodies

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Description

D-γ-Glu-Tyr is a D-isomer of γ-Glu-Tyr (HY-P4633), the difference being the γ-Glu content.γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet[1].

Molecular Weight

310.30

Formula

C14H18N2O6
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{D-γ-Glu}-Tyr
Sequence Shortening

{D-γ-Glu}-Y
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 12.5 mg/mL (40.28 mM; ultrasonic and adjust pH to 8 with NH3·H2O)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2227 mL 16.1134 mL 32.2269 mL
5 mM 0.6445 mL 3.2227 mL 6.4454 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.2227 mL 16.1134 mL 32.2269 mL 80.5672 mL
5 mM 0.6445 mL 3.2227 mL 6.4454 mL 16.1134 mL
10 mM 0.3223 mL 1.6113 mL 3.2227 mL 8.0567 mL
15 mM 0.2148 mL 1.0742 mL 2.1485 mL 5.3711 mL
20 mM 0.1611 mL 0.8057 mL 1.6113 mL 4.0284 mL
25 mM 0.1289 mL 0.6445 mL 1.2891 mL 3.2227 mL
30 mM 0.1074 mL 0.5371 mL 1.0742 mL 2.6856 mL
40 mM 0.0806 mL 0.4028 mL 0.8057 mL 2.0142 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-γ-Glu-Tyr Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-γ-Glu-Tyr2417507-97-0Drug IsomerDipeptidyl PeptidaseDPPInhibitorinhibitorinhibit

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