187 Results for "

AMC

" in MedChemExpress (MCE) Product Catalog:
Products (187)

187 Results for "AMC" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-P1002
CAS No.: 94367-21-2
Synonyms: Suc-LLVY-AMC
Research Areas:  

Others

Suc-Leu-Leu-Val-Tyr-AMC is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
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11
11 Cited Publications
Cat. No.: HY-P0019A
CAS No.: 2070009-61-7
Research Areas:  

Others

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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11
11 Cited Publications
Cat. No.: HY-P0019
CAS No.: 66216-78-2
Research Areas:  

Cardiovascular Disease

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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5
5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
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4
4 Cited Publications
Cat. No.: HY-D1670
CAS No.: 68542-93-8
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λex=380 nm, λem=465 nm) .
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3
3 Cited Publications
Cat. No.: HY-136626
CAS No.: 149697-16-5
Purity:  99.43%
Synonyms: Cbz-Ala-Ala-Asn-AMC
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .
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3
3 Cited Publications
Cat. No.: HY-123053
CAS No.: 348086-66-8
Purity:  99.91%
Synonyms: Z-LLE-AMC
Target:  

Proteasome

Research Areas:  

Neurological Disease

Z-Leu-Leu-Glu-AMC (Z-LLE-AMC) is a peptide-AMC linked substrate used to measure the postacidic-like hydrolysing activity of proteasome. Z-Leu-Leu-Glu-AMC can be used for the research of parkinson's disease .
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2
2 Cited Publications
Cat. No.: HY-134434
CAS No.: 136132-67-7
Purity:  99.79%
Research Areas:  

Others

Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .
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2
2 Cited Publications
Cat. No.: HY-137811
CAS No.: 88467-45-2
Purity:  99.07%
Synonyms: Suc-Ala-Ala-Pro-Phe-AMC
Target:  

Peptides

Research Areas:  

Others

Suc-AAPF-AMC is an α-chymotrypsin fluorogenic substrate for the quantitative determination of chymotrypsin activity .
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2
2 Cited Publications
Cat. No.: HY-N1181
CAS No.: 603-61-2
Synonyms: 4'-O-Methyl Quercetin
Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .
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2
2 Cited Publications
Cat. No.: HY-119323
CAS No.: 95633-27-5
Purity:  99.11%
Target:  

Fluorescent Dye

Research Areas:  

Others

7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
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1
1 Cited Publications
Cat. No.: HY-145983
CAS No.: 80049-85-0
Purity:  99.16%
Research Areas:  

Cancer

Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .
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1
1 Cited Publications
Cat. No.: HY-115391
CAS No.: 109358-46-5
Synonyms: Boc-Leu-Arg-Arg-AMC
Research Areas:  

Others

Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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1
1 Cited Publications
Cat. No.: HY-P2237
CAS No.: 65147-09-3
Research Areas:  

Endocrinology

Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays .
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1
1 Cited Publications
Cat. No.: HY-P2008
CAS No.: 65147-06-0
Synonyms: IEGR-AMC
Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
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1
1 Cited Publications
Cat. No.: HY-P4217
CAS No.: 201928-42-9
Target:  

Cathepsin

Research Areas:  

Others

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
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1
1 Cited Publications
Cat. No.: HY-134435
CAS No.: 70375-22-3
Purity:  99.2%
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
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1
1 Cited Publications
Cat. No.: HY-134961
CAS No.: 90468-18-1
Purity:  98.41%
Synonyms: Fluorogenic Proteasome Substrate; Z-ARR-AMC
Target:  

Proteasome

Research Areas:  

Others

Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .
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1
1 Cited Publications
Cat. No.: HY-134432B
Purity:  99.69%
Target:  

Ser/Thr Protease

Research Areas:  

Others

Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .
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1
1 Cited Publications
Cat. No.: HY-137834
CAS No.: 115035-46-6
Purity:  98.68%
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .
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