Z-Gly-Pro-Arg-AMC hydrochloride
Based on 2 publication(s) in Google Scholar
Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity.
For research use only. We do not sell to patients.
- Purity : 99.15%
- CAS No.: 201928-42-9
- Formula: C31H38ClN7O7
- Molecular Weight:656.13
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Z-Gly-Pro-Arg-AMC hydrochloride
MoreAll Cathepsin Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 201928-42-9
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Appearance Solid
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Molecular Weight 656.13
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Formula C31H38ClN7O7
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Color White to off-white
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Sequence
Z-Gly-Pro-Arg-AMC
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Sequence Shortening
Z-GPR-AMC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Expert Opin Drug Discov
Discovery of novel cathepsin K inhibitors for osteoporosis treatment using a deep learning-based strategy. [Abstract]2025 Oct;20(10):1345-1356. PMID: 40600916 -
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (152.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.5241 mL | 7.6204 mL | 15.2409 mL | 38.1022 mL |
| 5 mM | 0.3048 mL | 1.5241 mL | 3.0482 mL | 7.6204 mL | |
| 10 mM | 0.1524 mL | 0.7620 mL | 1.5241 mL | 3.8102 mL | |
| 15 mM | 0.1016 mL | 0.5080 mL | 1.0161 mL | 2.5401 mL | |
| 20 mM | 0.0762 mL | 0.3810 mL | 0.7620 mL | 1.9051 mL | |
| 25 mM | 0.0610 mL | 0.3048 mL | 0.6096 mL | 1.5241 mL | |
| 30 mM | 0.0508 mL | 0.2540 mL | 0.5080 mL | 1.2701 mL | |
| 40 mM | 0.0381 mL | 0.1905 mL | 0.3810 mL | 0.9526 mL | |
| 50 mM | 0.0305 mL | 0.1524 mL | 0.3048 mL | 0.7620 mL | |
| 60 mM | 0.0254 mL | 0.1270 mL | 0.2540 mL | 0.6350 mL | |
| 80 mM | 0.0191 mL | 0.0953 mL | 0.1905 mL | 0.4763 mL | |
| 100 mM | 0.0152 mL | 0.0762 mL | 0.1524 mL | 0.3810 mL |
Z-Gly-Pro-Arg-AMC hydrochloride Related Classifications
HY-P4217 Related Classifications
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