Z-Gly-Pro-Arg-AMC hydrochloride

Cat. No.: HY-P4217 Purity: 98.60%: FAQs
Data Sheet SDS COA Handling Instructions

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Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Gly-Pro-Arg-AMC hydrochloride Chemical Structure

CAS No. : 201928-42-9

Size Price Stock Quantity

1 mg USD 70 In-stock

Estimated Time of Arrival: December 31

5 mg USD 175 In-stock

Estimated Time of Arrival: December 31

10 mg USD 280 In-stock

Estimated Time of Arrival: December 31

50 mg Get quote

100 mg Get quote

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Z-Gly-Pro-Arg-AMC hydrochloride Related Antibodies

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Purity & Documentation

References

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Description

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity^[1]^[2].

Molecular Weight
656.13

Formula
C₃₁H₃₈ClN₇O₇

CAS No.
201928-42-9

Appearance

Solid

Color

White to off-white

Sequence
Z-Gly-Pro-Arg-AMC

Sequence Shortening
Z-GPR-AMC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years

-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro:

DMSO : 100 mg/mL (152.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass 1 mg 5 mg 10 mg

1 mM 1.5241 mL 7.6204 mL 15.2409 mL

5 mM 0.3048 mL 1.5241 mL 3.0482 mL

10 mM 0.1524 mL 0.7620 mL 1.5241 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

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Concentration

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Volume

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Molecular Weight *

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

C1

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Volume _(start)

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Concentration _(final)

C2

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage
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(per animal)
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(per animal)
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.60%
Select Batch:

Data Sheet (272 KB) SDS (393 KB)
COA (251 KB) RP-HPLC (110 KB) MS (216 KB)
Handling Instructions (2659 KB)

References

[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292. [Content Brief]

[2]. Li WA, et al. Detection of femtomole quantities of mature cathepsin K with zymography. Anal Biochem. 2010 Jun 1;401(1):91-8. [Content Brief]

[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292.

[2]. Li WA, et al. Detection of femtomole quantities of mature cathepsin K with zymography. Anal Biochem. 2010 Jun 1;401(1):91-8.

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg

DMSO 1 mM 1.5241 mL 7.6204 mL 15.2409 mL 38.1022 mL

5 mM 0.3048 mL 1.5241 mL 3.0482 mL 7.6204 mL

10 mM 0.1524 mL 0.7620 mL 1.5241 mL 3.8102 mL

15 mM 0.1016 mL 0.5080 mL 1.0161 mL 2.5401 mL

20 mM 0.0762 mL 0.3810 mL 0.7620 mL 1.9051 mL

25 mM 0.0610 mL 0.3048 mL 0.6096 mL 1.5241 mL

30 mM 0.0508 mL 0.2540 mL 0.5080 mL 1.2701 mL

40 mM 0.0381 mL 0.1905 mL 0.3810 mL 0.9526 mL

50 mM 0.0305 mL 0.1524 mL 0.3048 mL 0.7620 mL

60 mM 0.0254 mL 0.1270 mL 0.2540 mL 0.6350 mL

80 mM 0.0191 mL 0.0953 mL 0.1905 mL 0.4763 mL

100 mM 0.0152 mL 0.0762 mL 0.1524 mL 0.3810 mL

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Z-Gly-Pro-Arg-AMC hydrochloride Related Classifications

Metabolic Enzyme/Protease

Cathepsin

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Gly-Pro-Arg-AMC201928-42-9 Cathepsincathepsin KtrypsinsubstrateInhibitorinhibitorinhibit

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Remarks

Size	Price	Stock	Quantity
1 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 175	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 280	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

DMSO	1 mM	1.5241 mL	7.6204 mL	15.2409 mL	38.1022 mL
	5 mM	0.3048 mL	1.5241 mL	3.0482 mL	7.6204 mL
	10 mM	0.1524 mL	0.7620 mL	1.5241 mL	3.8102 mL
	15 mM	0.1016 mL	0.5080 mL	1.0161 mL	2.5401 mL
	20 mM	0.0762 mL	0.3810 mL	0.7620 mL	1.9051 mL
	25 mM	0.0610 mL	0.3048 mL	0.6096 mL	1.5241 mL
	30 mM	0.0508 mL	0.2540 mL	0.5080 mL	1.2701 mL
	40 mM	0.0381 mL	0.1905 mL	0.3810 mL	0.9526 mL
	50 mM	0.0305 mL	0.1524 mL	0.3048 mL	0.7620 mL
	60 mM	0.0254 mL	0.1270 mL	0.2540 mL	0.6350 mL
	80 mM	0.0191 mL	0.0953 mL	0.1905 mL	0.4763 mL
	100 mM	0.0152 mL	0.0762 mL	0.1524 mL	0.3810 mL

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Z-Gly-Pro-Arg-AMC hydrochloride

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