country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-100231

Copy Link Print Information

Cathepsin inhibitor 1

Name: Cathepsin inhibitor 1
Brand: MedChemExpress
SKU: HY-100231
Price: 120.00 USD
Availability: InStock
Rating: 5 (2 reviews)

2 Cited Publications

고객리뷰

Based on 2 publication(s) in Google Scholar

Cathepsin inhibitor 1 (Compound 25) is a potent and selective inhibitor of Cathepsin, with pIC₅₀s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively. Cathepsin inhibitor 1 is promising for research of osteoarthritis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity : 99.28%
CAS No.: 225120-65-0
화학식: C₂₀H₂₄ClN₅O₂
분자량:401.89

보관:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Cathepsin inhibitor 1 Chemical Structure

CAS No.: 225120-65-0

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
Publications (2)
용액&용해도
- In Vitro
순도&문서
References
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Cathepsin Isoforms :

In Vitro

The CatL pIC₅₀ value of Cathepsin inhibitor 1^[1]

Compd	CatL pIC₅₀	CatL2 pIC₅₀	CatS pIC₅₀	CatK pIC₅₀	CatB pIC₅₀
Cathepsin inhibitor 1	7.9	6.7	6.0	5.5	5.2

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 225120-65-0
Appearance Solid
분자량 401.89
화학식 C₂₀H₂₄ClN₅O₂
Color White to off-white
SMILES

O=C(C1=CC(C(C)(C)C)=NN1C)N[C@@H](CC2=CC=CC(Cl)=C2)C(NCC#N)=O
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (2)

All

Sort by:

Journal Impact Factor

Vita

2026 Apr 7.
Research Square Print

2025 May 28.

용액&용해도

In Vitro:

DMSO : 100 mg/mL (248.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4882 mL

12.4412 mL

24.8824 mL

5 mM

0.4976 mL

2.4882 mL

4.9765 mL

10 mM

0.2488 mL

1.2441 mL

2.4882 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Asaad N, et, al. Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4882 mL	12.4412 mL	24.8824 mL	62.2061 mL
	5 mM	0.4976 mL	2.4882 mL	4.9765 mL	12.4412 mL
	10 mM	0.2488 mL	1.2441 mL	2.4882 mL	6.2206 mL
	15 mM	0.1659 mL	0.8294 mL	1.6588 mL	4.1471 mL
	20 mM	0.1244 mL	0.6221 mL	1.2441 mL	3.1103 mL
	25 mM	0.0995 mL	0.4976 mL	0.9953 mL	2.4882 mL
	30 mM	0.0829 mL	0.4147 mL	0.8294 mL	2.0735 mL
	40 mM	0.0622 mL	0.3110 mL	0.6221 mL	1.5552 mL
	50 mM	0.0498 mL	0.2488 mL	0.4976 mL	1.2441 mL
	60 mM	0.0415 mL	0.2074 mL	0.4147 mL	1.0368 mL
	80 mM	0.0311 mL	0.1555 mL	0.3110 mL	0.7776 mL
	100 mM	0.0249 mL	0.1244 mL	0.2488 mL	0.6221 mL

Bioz

Keywords

Cathepsin inhibitor 1

2 Cited Publications

100 mg 견적 받기

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
Publications (2)
용액&용해도
- In Vitro
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

Cathepsin inhibitor 1

Publications Citing Use of MedChemExpress (MCE) Cathepsin inhibitor 1

All Cathepsin Isoforms