225120-65-0

Cathepsin inhibitor 1 Chemical Structure
225120-65-0

Chemical Structure

Cathepsin inhibitor 1

  • CAS No.: 225120-65-0
  • Formula:C20H24ClN5O2
  • Molecular Weight:401.89

IUPAC Name: (S)-3-(tert-butyl)-N-(3-(3-chlorophenyl)-1-((cyanomethyl)amino)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide

InChIKey: MZRVIHRERYCHBL-HNNXBMFYSA-N

SMILES: O=C(C1=CC(C(C)(C)C)=NN1C)N[C@@H](CC2=CC=CC(Cl)=C2)C(NCC#N)=O

Biological Activity: Cathepsin inhibitor 1 (Compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively. Cathepsin inhibitor 1 is promising for research of osteoarthritis[1].

Cat. No. Product Name Purity Description Pricing
HY-100231 		Cathepsin inhibitor 1 99.28% Cathepsin inhibitor 1 (Compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively. Cathepsin inhibitor 1 is promising for research of osteoarthritis.
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