66216-78-2
66216-78-2
Chemical Structure
Z-Gly-Gly-Arg-AMC
- CAS No.: 66216-78-2
- Formula:C28H33N7O7
- Molecular Weight:579.60
IUPAC Name: benzyl (S)-(2-((2-((5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-2-oxoethyl)carbamate
InChIKey: SXTGIAYWYXVNLT-NRFANRHFSA-N
SMILES: O=C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)=O)=O)OCC3=CC=CC=C3
Biological Activity: Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Z-Gly-Gly-Arg-AMC | 99.98% | Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm). | ||||||||||||||||||||
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References
- [1]. Tarandovskiy ID, et al. Antiplatelet agents can promote two-peaked thrombin generation in platelet rich plasma: mechanism and possible applications. PLoS One. 2013;8(2):e55688. [Content Brief]
- [2]. Machlus KR, et al. Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram. Thromb Haemost. 2009 Nov;102(5):936-44. [Content Brief]
Keywords
