1 Result for "

AY-22989 (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "AY-22989 (Standard)" in MCE Product Catalog:

Cat. No.: HY-10219R
CAS No.: 53123-88-9
Synonyms: Sirolimus (Standard); AY-22989 (Standard); NSC 226080 (Standard)
Rapamycin (Standard) (Sirolimus (Standard)) is the analytical standard of Rapamycin (HY-10219). This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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