9 Results for "

Mercaptospironolactone

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Mercaptospironolactone" in MCE Product Catalog:

Cat. No.: HY-P3990
CAS No.: 1029227-48-2
Target:  

VEGFR Autophagy Apoptosis

Research Areas:  

Cancer

Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts .
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Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Target:  

MMP

Research Areas:  

Others

MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
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Cat. No.: HY-P4397
CAS No.: 115499-13-3
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .
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Cat. No.: HY-130465
CAS No.: 38753-76-3
Purity:  99.85%
Synonyms: Deacetylspironolactone; Mercaptospironolactone
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

7α-Thiospironolactone is the transformation product of spironolactone (HY-B0561), which can be obtained by the metabolism of Thermomyces lanuginosus .
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Cat. No.: HY-P1193
CAS No.: 129623-01-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

GR 82334 is a potent and specific reversible tachykinin NK1 receptor antagonist . GR 82334 inhibits substance P-induced sensitization by blocking SP NK1 receptors in naked mole-rats .
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Cat. No.: HY-P1162
CAS No.: 73168-24-8
Synonyms: SKF 100273
Target:  

Vasopressin Receptor

Research Areas:  

Metabolic Disease

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .
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Cat. No.: HY-P1720
CAS No.: 19246-24-3
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
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Cat. No.: HY-P1709
CAS No.: 141912-59-6
Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model .
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Cat. No.: HY-P11022
CAS No.: 55599-68-3
Synonyms: A-3302-B
Research Areas:  

Infection Cancer

TL-119 (A-3302-B) is a polypeptide. TL-119 can be isolated from the bacteria Micromonospora sp. MAG 9-7 and Saccharomonospora sp. CNQ-490. TL-119 inhibits TRPV-1. TL-119 exhibits antiviral activity against HSV-2. TL-119 possesses anticancer activity against gastric cancer and colorectal cancer .
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