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2 Results for "
THIP hydrochloride (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "THIP hydrochloride (Standard)" in MCE Product Catalog:
Cat. No.: HY-10232R
CAS No.: 64603-91-4
Synonyms: Gaboxadol (Standard)
Target:
Research Areas:
THIP (Gaboxadol) Standard is the analytical standard of THIP (HY-10232). This product is intended for research and analytical applications. THIP (Gaboxadol) is a blood-brain barrier-penetrant, orally active selective GABAA receptor agonist. THIP exhibits EC50 values of 33 μM and 130 μM for α4β2δ and α4β1δ receptors, respectively. THIP activates extrasynaptic GABAA receptors to produce tonic inhibition and inhibits GABAergic interneurons to cause disinhibition. THIP is used in research on insomnia, sleep disorders, and addictive behaviors .
Cat. No.: HY-10233R
CAS No.: 85118-33-8
Synonyms: Lu 02-030 hydrochloride (Standard); THIP hydrochloride (Standard)
Target:
Research Areas:
Gaboxadol (hydrochloride) (Standard) is the analytical standard of Gaboxadol (hydrochloride). This product is intended for research and analytical applications. Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 μM, a full agonist efficacy at α5 subunit (ED50=28-129 μM) and a superagonist efficacy at α4β3δ (ED50=6 μM). Gaboxadol hydrochloride is a non-opioid agent .
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