THIP (Standard)
THIP (Gaboxadol) Standard is the analytical standard of THIP (HY-10232). This product is intended for research and analytical applications. THIP (Gaboxadol) is a blood-brain barrier-penetrant, orally active selective GABAA receptor agonist. THIP exhibits EC50 values of 33 μM and 130 μM for α4β2δ and α4β1δ receptors, respectively. THIP activates extrasynaptic GABAA receptors to produce tonic inhibition and inhibits GABAergic interneurons to cause disinhibition. THIP is used in research on insomnia, sleep disorders, and addictive behaviors.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 64603-91-4
- Formula: C6H8N2O2
- Molecular Weight:140.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 64603-91-4
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Molecular Weight 140.14
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Formula C6H8N2O2
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SMILES
O=C1C2=C(CNCC2)ON1
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Synonyms
Gaboxadol (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- THIP (Standard)
- 64603-91-4
- Gaboxadol (Standard)
- Reference Standards
- GABA Receptor
- Gamma-aminobutyric acid Receptor
- γ-Aminobutyric acid Receptor
- VTA dopamine neurons
- SLC36A1
- extrasynaptic delta-subunit-containing GABAA receptors
- mouse neocortical layer 2/3 neurons
- hPAT1
- GABAA receptor
- rOat1
- Slc22a6
- Xenopus oocytes
- Caco-2 cell monolayers
- Inhibitor
- inhibitor
- inhibit