1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. THIP

THIP (Synonyms: Gaboxadol)

Cat. No.: HY-10232 Purity: 99.36%
Handling Instructions

THIP (Gaboxadol) is a selective δ-aminobutyric acid type A receptor (δ-GABAAR) agonist, functionally selective GABAAR ligand, exhibits agonism at α4β1δ, α4β3δ and weak antagonism at αβγ and α4β2δ GABAARs.

For research use only. We do not sell to patients.

THIP Chemical Structure

THIP Chemical Structure

CAS No. : 64603-91-4

Size Price Stock Quantity
10 mM * 1 mL in Water USD 99 In-stock
Estimated Time of Arrival: December 31
25 mg USD 90 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

THIP (Gaboxadol) is a selective δ-aminobutyric acid type A receptor (δ-GABAAR) agonist, functionally selective GABAAR ligand, exhibits agonism at α4β1δ, α4β3δ and weak antagonism at αβγ and α4β2δ GABAARs[1].

IC50 & Target

α4β3δ GABAAR

13 μM (EC50)

Clinical Trial
Molecular Weight

140.14

Formula

C₆H₈N₂O₂

CAS No.

64603-91-4

SMILES

O=C1C2=C(CNCC2)ON1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 23.33 mg/mL (166.48 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1357 mL 35.6786 mL 71.3572 mL
5 mM 1.4271 mL 7.1357 mL 14.2714 mL
10 mM 0.7136 mL 3.5679 mL 7.1357 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

THIPGaboxadolGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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Product Name:
THIP
Cat. No.:
HY-10232
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