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Cat. No.: HY-10233R

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Gaboxadol hydrochloride (Standard)

(Synonyms: Lu 02-030 hydrochloride (Standard); THIP hydrochloride (Standard))

Gaboxadol (hydrochloride) (Standard) is the analytical standard of Gaboxadol (hydrochloride). This product is intended for research and analytical applications. Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 μM, a full agonist efficacy at α5 subunit (ED50=28-129 μM) and a superagonist efficacy at α4β3δ (ED50=6 μM). Gaboxadol hydrochloride is a non-opioid agent.

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CAS No.: 85118-33-8
화학식: C₆H₉ClN₂O₂
분자량:176.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Gaboxadol hydrochloride (Standard) Chemical Structure

CAS No.: 85118-33-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 85118-33-8
분자량 176.60
화학식 C₆H₉ClN₂O₂
SMILES

O=C1C2=C(CNCC2)ON1.Cl
Synonyms

Lu 02-030 hydrochloride (Standard); THIP hydrochloride (Standard)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Johnston GA, et al. Neurochemicals for the investigation of GABA(C) receptors. Neurochem Res. 2010 Dec;35(12):1970-7. [Content Brief]

[2]. Cogram P, et al. Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome.Front Behav Neurosci. 2019 Jun 25;13:141. [Content Brief]

[3]. Larsen M, et al. Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan.Br J Pharmacol. 2009 Aug;157(8):1380-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Gaboxadol hydrochloride (Standard)

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Gaboxadol hydrochloride (Standard)

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Gaboxadol hydrochloride (Standard) Related Classifications

HY-10233R Related Classifications